Lopes Dias João, Borges Alexandra, Lima Rego Rafaela
Department of Radiology, Hospital de São José, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.
Department of Radiology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal.
BJR Case Rep. 2016 Nov 2;2(4):20150276. doi: 10.1259/bjrcr.20150276. eCollection 2016.
Primary intraosseous squamous cell carcinoma is a rare malignant tumour that exclusively arises within the jaws. Its diagnosis requires an appropriate clinical, imaging and histological correlation. The exclusion of primary oral mucosa lesions and metastatic disease is mandatory. We report an atypical imaging appearance of this uncommon entity, characterized by new bone formation and periosteal reaction that resemble sarcomatous or malignant odontogenic tumours. A comprehensive discussion on the embryological principles of primary intraosseous squamous cell carcinoma is also provided.
原发性骨内鳞状细胞癌是一种罕见的恶性肿瘤,仅发生于颌骨内。其诊断需要恰当的临床、影像学及组织学相互关联。必须排除原发性口腔黏膜病变及转移性疾病。我们报告了这种罕见实体的一种不典型影像学表现,其特征为新骨形成和骨膜反应,类似于肉瘤或恶性牙源性肿瘤。本文还对原发性骨内鳞状细胞癌的胚胎学原理进行了全面讨论。