Hoi J W, Kim H K, Fong C J, Zweck L, Hielscher A H
Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, 500 W. 120th St., New York, NY 10027, USA.
Department of Radiology, Columbia University, 630 W. 168th St., New York, NY 10032, USA.
Biomed Opt Express. 2018 Oct 19;9(11):5597-5614. doi: 10.1364/BOE.9.005597. eCollection 2018 Nov 1.
A novel multi-view non-contact dynamic diffuse optical tomographic imaging system for the clinical evaluation of vasculature in the lower extremities is presented. The system design and implementation are described in detail, including methods for simultaneously obtaining and reconstructing diffusely reflected and transmitted light using a system of mirrors and a single CCD camera. The system and its performance using numeric simulations and optical phantoms. Measurements of a healthy foot in vivo demonstrates the potential of the system in assessing perfusion within the foot.
介绍了一种用于下肢血管临床评估的新型多视角非接触式动态漫射光学断层成像系统。详细描述了系统的设计和实现，包括使用反射镜系统和单个电荷耦合器件（CCD）相机同时获取和重建漫反射光和透射光的方法。通过数值模拟和光学体模对系统及其性能进行了研究。对健康足部的体内测量证明了该系统在评估足部灌注方面的潜力。
