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用于治疗慢性静脉闭塞性疾病的锐性再通术的方法、技术成功率、并发症及支架通畅情况:123例患者的经验

Approach, Technical Success, Complications, and Stent Patency of Sharp Recanalization for the Treatment of Chronic Venous Occlusive Disease: Experience in 123 Patients.

作者信息

McDevitt Joseph L, Srinivasa Ravi N, Gemmete Joseph J, Hage Anthony N, Srinivasa Rajiv N, Bundy Jacob J, Chick Jeffrey Forris Beecham

机构信息

Department of Radiology, Division of Vascular and Interventional Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.

Department of Interventional Radiology, University of California Los Angeles, 757 Westwood Plaza, Los Angeles, CA, 90095, USA.

出版信息

Cardiovasc Intervent Radiol. 2019 Feb;42(2):205-212. doi: 10.1007/s00270-018-2090-1. Epub 2018 Nov 20.

Abstract

PURPOSE

To report the technical success and complications following sharp recanalization of chronic venous occlusions.

MATERIALS AND METHODS

A total of 123 patients, including 75 (61.0%) men and 48 (39.0%) women, with mean age of 50.5 ± 17.5 years (range 19-90 years), underwent sharp recanalization of chronic venous occlusions. The etiologies of occlusion were chronic deep venous thrombosis (n = 43; 35.0%), prior central venous access (n = 39; 31.7%), indwelling cardiac leads (n = 21; 17.1%), and occluded venous stents (n = 20; 16.3%). The sites of venous occlusion included 59/123 (48.0%) thoracic central veins, 37 (30.1%) non-thoracic central veins, and 27 (22.0%) peripheral veins. Median length of occlusion was 3.2 ± 1.4 cm (range 1.3-10.9 cm).

RESULTS

Sharp recanalization was most commonly attempted with transseptal needles in 108/123 (87.8%), with a mean number of 1.2 ± 0.4 crossing devices per patient (range 1-4 devices). Targeting devices included a loop snare (n = 92; 74.8%), partially deployed Wallstent (n = 21; 17.1%), partially deployed Amplatzer vascular plug (n = 8; 6.5%), and an angioplasty balloon (n = 3; 2.4%). Technical success was achieved in 111 (90.2%) patients. There were 3 (2.4%) severe, 1 (0.8%) moderate, and 7 (5.7%) minor adverse events. Severe adverse events included 1 case each of pericardial tamponade, hemothorax, and inferior vena cava filter occlusion. 88 (71.5%) patients had venous stents placed; at the last follow-up examination, 68/86 (79.0%) stents were patent.

CONCLUSION

Sharp recanalization has a high technical success and low rate of adverse events in the recanalization of chronic venous occlusions.

摘要

目的

报告慢性静脉闭塞锐性再通术后的技术成功率及并发症情况。

材料与方法

123例患者接受了慢性静脉闭塞锐性再通术,其中男性75例(61.0%),女性48例(39.0%),平均年龄50.5±17.5岁(范围19 - 90岁)。闭塞病因包括慢性深静脉血栓形成(n = 43;35.0%)、既往中心静脉置管(n = 39;31.7%)、植入式心脏导线(n = 21;17.1%)以及闭塞的静脉支架(n = 20;16.3%)。静脉闭塞部位包括59/123(48.0%)例胸段中心静脉、37例(30.1%)非胸段中心静脉和27例(22.0%)外周静脉。闭塞的中位长度为3.2±1.4 cm(范围1.3 - 10.9 cm)。

结果

108/123(87.8%)例患者最常采用经间隔穿刺针进行锐性再通,每位患者平均使用1.2±0.4根穿刺器械(范围1 - 4根)。定位器械包括圈套器(n = 92;74.8%)、部分释放的Wallstent支架(n = 21;17.1%)、部分释放的Amplatzer血管封堵器(n = 8;6.5%)以及血管成形球囊(n = 3;2.4%)。111例(90.2%)患者获得技术成功。发生3例(2.4%)严重不良事件、1例(0.8%)中度不良事件和7例(5.7%)轻度不良事件。严重不良事件包括心包填塞、血胸和下腔静脉滤器闭塞各1例。88例(71.5%)患者置入了静脉支架;在最后一次随访检查时,86例中的68例(79.0%)支架通畅。

结论

慢性静脉闭塞再通术中,锐性再通技术成功率高,不良事件发生率低。

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