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[使用不同类型光敏剂的光动力疗法治疗基底细胞癌的疗效]

[Efficacy of photodynamic therapy for basal cell carcinoma using photosensitizers of different classes].

作者信息

Romanko Y S, Kaplan M A, Ivanov S A, Galkin V N, Molochkova Y V, Kuntsevich Z S, Tretiakova E I, Sukhova T E, Molochkov V A, Molochkov A V

出版信息

Vopr Onkol. 2016;62(3):447-50.

PMID:30462909
Abstract

The paper presented results of photodynamic therapy for 139 patients with basal cell carcinoma. We conducted a study of the efficacy and safety of four methods of photodynamic therapy. There were used the following photosensitizers: photohem, photosens, photolon and photodithazine. Photodynamic therapy using photosensitizers of chlorine series (photolon and photoditazin) provides a better long-term results improving disease-free 3-year survival rate to 90.4% and 92.3%, respectively compared to 54.7% and 71.1% in groups, in which treatment was restricted by photohem and photosens.

摘要

该论文展示了对139例基底细胞癌患者进行光动力治疗的结果。我们对四种光动力治疗方法的疗效和安全性进行了研究。使用了以下光敏剂:光血卟啉、光过敏素、光龙和光二嗪。与使用光血卟啉和光过敏素进行治疗的组相比,使用氯系光敏剂(光龙和光二嗪)的光动力治疗能带来更好的长期效果,将3年无病生存率分别提高到90.4%和92.3%,而前两组分别为54.7%和71.1%。

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引用本文的文献

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Optical coherence angiography for pre-treatment assessment and treatment monitoring following photodynamic therapy: a basal cell carcinoma patient study.光相干层析血管造影术在光动力疗法后的预处理评估和治疗监测中的应用:基底细胞癌患者研究。
Sci Rep. 2019 Dec 10;9(1):18670. doi: 10.1038/s41598-019-55215-6.
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Photodynamic Therapy for Cancer: What's Past is Prologue.光动力疗法治疗癌症:往事如昔,启示未来。
Photochem Photobiol. 2020 May;96(3):506-516. doi: 10.1111/php.13190. Epub 2020 Jan 7.