The Center for Applied Health Sciences, 4302 Allen Road, Suite 120, Stow, OH 44224, USA.
Exercise and Performance Nutrition Laboratory, School of Health Sciences, Lindenwood University, 209 S. Kingshighway, St. Charles, MO 63301, USA.
Nutrients. 2018 Nov 20;10(11):1807. doi: 10.3390/nu10111807.
(Ashwagandha) is an Ayurvedic herb categorized as having "rasayana" (rejuvenator), longevity, and revitalizing properties. Sensoril® is a standardized aqueous extract of the roots and leaves of . To examine the impact of Sensoril supplementation on strength training adaptations. Recreationally active men (26.5 ± 6.4 years, 181 ± 6.8 cm, 86.9 ± 12.5 kg, 24.5 ± 6.6% fat) were randomized in a double-blind fashion to placebo (PLA, = 19) or 500 mg/d Sensoril (S500, = 19). Body composition (DEXA), muscular strength, power, and endurance, 7.5 km cycling time trial, and clinical blood chemistries were measured at baseline and after 12 weeks of supplementation and training. Subjects were required to maintain their normal dietary habits and to follow a specific, progressive overload resistance-training program (4-day/week, upper body/lower body split). 2 × 2 mixed factorial ANOVA was used for analysis and statistical significance was set at ≤ 0.05. Gains in 1-RM squat (S500: +19.1 ± 13.0 kg vs. PLA +10.0 ± 6.2 kg, = 0.009) and bench press (S500: +12.8 ± 8.2 kg vs. PLA: +8.0 ± 6.0 kg, = 0.048) were significantly greater in S500. Changes in DEXA-derived android/gynoid ratio (S500: +0.0 ± 0.14 vs. PLA: +0.09 ± 0.1, = 0.03) also favored S500. No other between-group differences were found for body composition, visual analog scales for recovery and affect, or systemic hemodynamics, however, only the S500 group experienced statistically significant improvements in average squat power, peak bench press power, 7.5 km time trial performance, and perceived recovery scores. Clinical chemistry analysis indicated a slight polycythemia effect in PLA, with no other statistical or clinically relevant changes being noted. A 500 mg dose of an aqueous extract of Ashwagandha improves upper and lower-body strength, supports a favorable distribution of body mass, and was well tolerated clinically in recreationally active men over a 12-week resistance training and supplementation period.
（ Ashwagandha ）是一种阿育吠陀草药，被归类为具有“ Rasayana ”（ rejuvenator ）、长寿和振兴特性。 Sensoril ®是根和叶的标准化水性提取物。 为了研究 Sensoril 补充剂对力量训练适应性的影响。 有规律运动的男性（ 26.5 ± 6.4 岁， 181 ± 6.8 厘米， 86.9 ± 12.5 千克， 24.5 ± 6.6 ％脂肪）以双盲方式随机分为安慰剂（ PLA ， = 19 ）或 500mg/d Sensoril （ S500 ， = 19 ）。在基线和 12 周补充和训练后测量身体成分（ DEXA ）、肌肉力量、功率和耐力、 7.5km 骑自行车时间试验和临床血液化学。要求受试者保持正常的饮食习惯，并遵循特定的、渐进的超负荷抗阻训练计划（ 4 天/周，上身/下身分裂）。使用 2 × 2 混合方差分析进行分析，统计显著性设为 ≤ 0.05 。 S500 深蹲 1RM 增加（ S500 ： +19.1 ± 13.0kg 与 PLA ： +10.0 ± 6.2kg ， = 0.009 ）和卧推（ S500 ： +12.8 ± 8.2kg 与 PLA ： +8.0 ± 6.0kg ， = 0.048 ）显著大于 S500 。 DEXA 衍生的安卓/女阴比例的变化（ S500 ： +0.0 ± 0.14 与 PLA ： +0.09 ± 0.1 ， = 0.03 ）也有利于 S500 。然而，只有 S500 组在平均深蹲功率、峰值卧推功率、 7.5km 时间试验性能和感知恢复评分方面有统计学显著改善。临床化学分析表明 PLA 有轻微的红细胞增多症效应，没有其他统计学或临床相关变化。 500mg 剂量的 Ashwagandha 水提物可提高上下肢力量，支持身体质量的有利分布，在 12 周抗阻训练和补充期间，在有规律运动的男性中具有良好的临床耐受性。
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