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手部外科中的抗生素使用:外科医生的决策制定和对现有证据的遵循。

Antibiotic Use in Hand Surgery: Surgeon Decision Making and Adherence to Available Evidence.

机构信息

Walter Reed National Military Medical Center, Bethesda, MD, USA.

The Curtis National Hand Center, Baltimore, MD, USA.

出版信息

Hand (N Y). 2020 Jul;15(4):534-541. doi: 10.1177/1558944718812161. Epub 2018 Nov 22.

Abstract

There are no clearly defined guidelines from hand surgical societies regarding preoperative antibiotic prophylaxis. Many hand surgeons continue to routinely use preoperative prophylaxis with limited supporting evidence. This study aimed to determine for which scenarios surgeons give antibiotics, the reasons for administration, and whether these decisions are evidence-based. An anonymous 25-question survey was e-mailed to the 921-member American Society for Surgery of the Hand listserv. We collected demographic information; participants were asked whether they would administer antibiotics in a number of surgical scenarios and for what reasons. Respondents were broken into 3 groups based on when they said they would administer antibiotics: Group 1 (40 respondents) would give antibiotics in the case of short cases, healthy patients, without hardware; group 2 (9 respondents) would not give antibiotics in any scenario; and group 3 (129 respondents) would give antibiotics situationally. The Fisher exact test compared demographic variables, frequency of use, and indications of antibiotic prophylaxis. Of the 921 recipients, 178 (19%) responded. Demographic variables did not correlate with the antibiotic use group. Operative case time >60 minutes, medical comorbidity, and pinning each increased antibiotic use. Group 1 respondents were more likely to admit that their practice was not evidence-based (74.4%) and that they gave antibiotics for medical-legal concern (75%). Twenty-two percent of respondents reported seeing a complication from routine prophylaxis, including infection. Antibiotics are still given unnecessarily before hand surgery, most often for medical-legal concern. Clear guidelines for preoperative antibiotic use may help reduce excessive and potentially inappropriate treatment and provide medical-legal support.

摘要

手部外科学会并没有针对术前抗生素预防的明确指南。许多手部外科医生仍然常规使用术前预防措施,但支持证据有限。本研究旨在确定外科医生在哪些情况下使用抗生素、使用的原因,以及这些决策是否基于证据。我们向美国手部外科学会的 921 名成员列表服务发送了一封匿名的 25 个问题的电子邮件调查。我们收集了人口统计学信息;要求参与者在一些手术场景下是否会使用抗生素以及原因。根据他们表示会使用抗生素的时间,受访者被分为 3 组:第 1 组(40 名受访者)会在短时间手术、健康患者、无内置物的情况下使用抗生素;第 2 组(9 名受访者)不会在任何情况下使用抗生素;第 3 组(129 名受访者)会根据情况使用抗生素。Fisher 精确检验比较了人口统计学变量、使用频率和抗生素预防指征。在 921 名收件人中,有 178 人(19%)做出了回应。人口统计学变量与抗生素使用组无关。手术时间>60 分钟、合并症和钢针固定都会增加抗生素的使用。第 1 组的受访者更有可能承认他们的做法没有基于证据(74.4%),并且他们出于医疗法律方面的考虑使用抗生素(75%)。22%的受访者报告说他们看到了常规预防措施引起的并发症,包括感染。手部外科手术前仍不必要地使用抗生素,最常见的原因是出于医疗法律方面的考虑。明确的术前抗生素使用指南可能有助于减少过度和潜在不适当的治疗,并提供医疗法律支持。

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