Marek M, Grobe-Einsler M, Bedarf J R, Wabbels B, Paus S
Department of Neurology, University of Bonn, Bonn, Germany,
Department of Ophthalmology, University of Bonn, Bonn, Germany.
Neuropsychiatr Dis Treat. 2018 Oct 26;14:2847-2852. doi: 10.2147/NDT.S175193. eCollection 2018.
Sexual dysfunction is a frequent, yet underrated, symptom of neurological disease. While knowledge of non-motor comorbidity in focal dystonia is growing rapidly, there is no information on the prevalence of sexual dysfunction in cervical dystonia (CD) or blepharospasm (BL).
In this controlled study, we examined sexual dysfunction in 65 patients with CD and 54 patients with BL by the Arizona Sexual Experience Scale, a validated self-rating scale.
Sexual dysfunction was significantly higher in CD patients (45%) than in controls (24%), and frequent in BL (39%). Interestingly, variables of dystonia such as disease duration or severity did not influence sexuality; yet, 23% of CD patients ascribed worsening of their sexual life to dystonia. Symptoms of depression were identified as the most important predictors for sexual dysfunction, followed by age, and personal status (single).
Our observations establish sexual dysfunction as a frequent non-motor symptom in CD and BL that is perceived as a burden. It should be considered when investigating patients with adult-onset focal dystonia.
性功能障碍是神经疾病常见但被低估的症状。虽然局灶性肌张力障碍中非运动合并症的知识增长迅速，但关于颈部肌张力障碍（CD）或眼睑痉挛（BL）中性功能障碍患病率的信息却尚无报道。
在这项对照研究中，我们通过亚利桑那性体验量表（一种经过验证的自评量表）对65例CD患者和54例BL患者的性功能障碍进行了检查。
CD患者的性功能障碍发生率（45%）显著高于对照组（24%），BL患者中也较为常见（39%）。有趣的是，肌张力障碍的变量如病程或严重程度并未影响性功能；然而，23%的CD患者将其性生活变差归因于肌张力障碍。抑郁症状被确定为性功能障碍的最重要预测因素，其次是年龄和个人状况（单身）。
我们的观察结果表明，性功能障碍是CD和BL中常见的非运动症状，且被视为一种负担。在对成年发病的局灶性肌张力障碍患者进行调查时应予以考虑。
