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腹腔镜辅助全结直肠切除术治疗家族性腺瘤性息肉病(FAP)。

Laparoscopy adjuvant total colorectal resection for the treatment of familial adenomatous polyposis (FAP).

机构信息

Department of Colorectal Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Tianjin, 300121, People's Republic of China.

Department of Pathology, Tianjin Medical University General Hospital, Tianjin, 300052, China.

出版信息

Clin Transl Oncol. 2019 Jun;21(6):753-759. doi: 10.1007/s12094-018-1979-0. Epub 2018 Nov 21.

Abstract

OBJECTIVE

To discuss and evaluate the safety and value of laparoscopy adjuvant total colorectal resection for the treatment of familial adenomatous polyposis (FAP).

METHODS

From March 2010 to June 2015, 38 cases were retrospectively analyzed and divided into 2 groups, of which 17 cases used laparoscopy adjuvant total colorectal resection, and 21 cases used conventional laparotomy. Clinical data were obtained, and the safety and prognosis were observed.

RESULTS

Seventeen cases using laparoscopy adjuvant total colorectal resection achieved success with no conversion to laparotomy and intraoperative complications. There was no significant difference in operation time between the two groups. There were significant differences in blood loss, the length of incision, postoperative recovery time of intestinal function and postoperative hospital stay between the two groups (P < 0.05). The trauma in laparoscopy group was less, and could recover faster, and there was no significant difference in complications between the two groups. In addition, there were no recurrence, distant metastasis and death in the follow-up period from 6 to 56 months.

CONCLUSION

Laparoscopy adjuvant total colorectal resection is more safe and feasible, which has minimal invasion and can recover fast.

摘要

目的

探讨和评估腹腔镜辅助全结肠直肠切除术治疗家族性腺瘤性息肉病(FAP)的安全性和价值。

方法

回顾性分析 2010 年 3 月至 2015 年 6 月收治的 38 例 FAP 患者,分为腹腔镜辅助全结肠直肠切除术组(腹腔镜组)17 例和传统开腹手术组 21 例。比较两组患者的临床资料,观察安全性和预后。

结果

腹腔镜组 17 例手术均顺利完成,无中转开腹,无术中并发症。两组手术时间比较差异无统计学意义。腹腔镜组术中出血量、切口长度、术后肠功能恢复时间、术后住院时间均明显少于开腹组(P<0.05)。腹腔镜组创伤更小,术后恢复更快,两组并发症发生率比较差异无统计学意义。随访 6~56 个月,两组均无复发、远处转移及死亡。

结论

腹腔镜辅助全结肠直肠切除术治疗 FAP 安全可行,创伤小,恢复快。

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