Deklerk J, Benzer H, Haider W, Pauser G, Stellwag F
Anaesthesist. 1977 Dec;26(12):639-43.
During extracorporeal circulation for open heart surgery an activation of the kininogen-kininsystem occurs with a decrease in plasma-kininogen-levels significantly exceeding the effect of haemodilution, and thus being due to an increased liberation of kinin. This effect could be suppressed by kallikrein inhibition by means of a protease-inhibitor.
在心脏直视手术的体外循环过程中，激肽原 - 激肽系统被激活，血浆激肽原水平下降，其下降幅度显著超过血液稀释的影响，因此是由于激肽释放增加所致。这种效应可通过蛋白酶抑制剂抑制激肽释放酶来加以抑制。
