Park D L, Lee L S, Price R L, Pohland A E
Food and Drug Administration, Center for Food Safety and Applied Nutrition, Washington, DC 20204.
J Assoc Off Anal Chem. 1988 Jul-Aug;71(4):685-703.
Ammoniation of corn, peanuts, cottonseed, and meals to alter the toxic and carcinogenic effects of aflatoxin contamination has been the subject of intense research effort by scientists in various government agencies and universities, both in the United States and abroad. Results of these studies have been well documented over the last 20 years. Engineers have devised workable systems of treatment of whole seeds, kernels, or meals; chemists have identified and characterized products formed from the reaction of aflatoxin B1 with ammonia with and without a meal matrix; biochemists have studied the biological effects of these compounds in model systems; and nutritionists have studied animal responses to rations containing ammoniated or non-ammoniated components. This review describes these studies. Results demonstrate overwhelming support for the efficacy and safety of ammoniation as a practical solution to aflatoxin detoxification in animal feeds.
对玉米、花生、棉籽及粕类进行氨化处理以改变黄曲霉毒素污染所产生的毒性和致癌作用，一直是美国国内外各政府机构和大学的科学家们深入研究的课题。在过去20年里，这些研究结果已有充分记录。工程师们设计出了可行的处理完整种子、果仁或粕类的系统；化学家们已鉴定并表征了黄曲霉毒素B1与氨在有无粕类基质情况下反应所形成的产物；生物化学家们在模型系统中研究了这些化合物的生物学效应；营养学家们则研究了动物对含有氨化或未氨化成分日粮的反应。本综述描述了这些研究。结果表明，氨化作为动物饲料中黄曲霉毒素解毒的一种切实可行的解决办法，其有效性和安全性获得了压倒性的支持。
