基于石墨烯的仿生组织再生支架

Graphene-Functionalized Biomimetic Scaffolds for Tissue Regeneration.

机构信息

Research Center for Energy Convergence Technology, Pusan National University, Busan, South Korea.

Department of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan, South Korea.

出版信息

Adv Exp Med Biol. 2018;1064:73-89. doi: 10.1007/978-981-13-0445-3_5.

DOI:10.1007/978-981-13-0445-3_5

PMID:30471027

Abstract

Graphene is a two-dimensional atomic layer of graphite, where carbon atoms are assembled in a honeycombed lattice structure. Recently, graphene family nanomaterials, including pristine graphene, graphene oxide and reduced graphene oxide, have increasingly attracted a great deal of interest from researchers in a variety of science, engineering and industrial fields because of their unique structural and functional features. In particular, extensive studies have been actively conducted in the biomedical and related fields, including multidisciplinary and emerging areas, as their stimulating effects on cell behaviors have been becoming an increasing concern. Herein, we are attempting to summarize some of recent findings in the fields of tissue regeneration concerning the graphene family nanomaterial-functionalized biomimetic scaffolds, and to provide the promising perspectives for the possible applications of graphene family nanomaterial.

摘要

石墨烯是石墨的二维原子层，碳原子组装成蜂窝状晶格结构。最近，包括原始石墨烯、氧化石墨烯和还原氧化石墨烯在内的石墨烯家族纳米材料因其独特的结构和功能特性而引起了科学界、工程界和工业界的广泛关注。特别是，由于其对细胞行为的刺激作用越来越受到关注，生物医学及相关领域，包括多学科和新兴领域，已经积极开展了广泛的研究。在此，我们试图总结一些关于组织再生领域的最新发现，即石墨烯家族纳米材料功能化仿生支架，并为石墨烯家族纳米材料的可能应用提供有前景的观点。