Laurentaci G, Dioguardi D, Pascone M
Arch Sci Med (Torino). 1977 Jul-Sep;134(3):275-81.
Considering the immunodepressive properties of aprotinine, the influence of this protease inhibitor on the induction of methylcholanthrene sarcoma in rats has been investigated. The results of the investigation showed that aprotinine failed to modify the experimental tumour induction process. This observation provides further confirmation that immunodepression is not a position to favour the growth of a tumour as a result of chemically induced oncogenesis.
鉴于抑肽酶的免疫抑制特性，已对这种蛋白酶抑制剂对大鼠甲基胆蒽肉瘤诱导的影响进行了研究。研究结果表明，抑肽酶未能改变实验性肿瘤诱导过程。这一观察结果进一步证实，免疫抑制并非因化学诱导肿瘤发生而有利于肿瘤生长的因素。
