Department of Forest Biomaterials , NC State University , Campus Box 8005, Raleigh , North Carolina 27695 , United States.
Department of Entomology and Plant Pathology , NC State University , Campus Box 7616, Raleigh , North Carolina 27695 , United States.
Langmuir. 2019 Jan 8;35(1):104-112. doi: 10.1021/acs.langmuir.8b02655. Epub 2018 Dec 6.
A heightened need to control the spread of infectious diseases prompted the current work in which functionalized and innovative antimicrobial tissue paper was developed with a hydrophobic spray-coating of chitosan (Ch) and cellulose nanocrystals (CNCs) composite. It was hypothesized that the hydrophobic nature of chitosan could be counterbalanced by the addition of CNC to maintain fiber formation and water absorbency. Light-weight tissue handsheets were prepared, spray-coated with Ch, CNC, and their composite coating (ChCNC), and tested for antimicrobial activity against Gram-negative bacteria Escherichia coli and a microbial sample from a human hand after using the rest room. Water absorption and strength properties were also analyzed. To activate the surface of cationized tissue paper, an oxygen/helium gas atmospheric plasma treatment was employed on the best performing antimicrobial tissue papers. The highest bactericidal activity was observed with ChCNC-coated tissue paper, inhibiting up to 98% microbial growth. Plasma treatment further improved the antimicrobial activity of the coatings. Water absorption properties were reduced with Ch but increased with CNC. This "self-disinfecting" bactericidal tissue has the potential to be one of the most innovative products for the hygiene industry because it can dry, clean, and resist the infection of surfaces simultaneously, providing significant societal benefits.
为了控制传染病的传播，我们开展了目前的工作，制备了具有抗菌功能的创新抗菌纸巾，其方法是在壳聚糖（Ch）和纤维素纳米晶体（CNCs）复合材料上进行疏水喷涂。我们假设，通过添加 CNC 可以平衡壳聚糖的疏水性，以保持纤维形成和吸水性。我们制备了轻质纸巾，并对其进行了 Ch、CNC 及其复合涂层（ChCNC）的喷涂，然后对其进行了抗菌活性测试，以评估其对革兰氏阴性菌大肠杆菌和人体手部微生物样本的抑制作用，这些样本是在使用完洗手间后收集的。此外，我们还分析了其吸水性和强度性能。为了激活阳离子化纸巾的表面，我们对具有最佳抗菌性能的纸巾进行了氧气/氦气大气压等离子体处理。ChCNC 涂层的纸巾具有最高的杀菌活性，抑制了高达 98%的微生物生长。等离子体处理进一步提高了涂层的抗菌活性。Ch 会降低纸巾的吸水性，但会增加 CNC 的吸水性。这种“自消毒”杀菌纸巾有可能成为卫生行业最具创新性的产品之一，因为它可以同时干燥、清洁和抵抗表面感染，为社会带来重大利益。
