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胎盘李斯特菌病合并绒毛膜羊膜炎的挑战性管理:2例病例的经验教训

Challenging management of chorioamnionitis with placental listeriosis: lessons from 2 cases.

作者信息

Park Ji Hyun, Ahn Jung Hwan, Seo Kyung Jin, Choi Sae Kyung, Park In Yang, Kim Yeon-Hee

机构信息

Department of Obstetrics and Gynecology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, Uijeongbu, Korea.

Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.

出版信息

Obstet Gynecol Sci. 2018 Nov;61(6):688-692. doi: 10.5468/ogs.2018.61.6.688. Epub 2018 Oct 11.

Abstract

Listeriosis is a rare foodborne infection caused by . It is 12-20 times more prevalent in pregnant women compared to the general population, with a 20-40% mortality rate in neonates. Early treatment with appropriate antimicrobial agents is critical for pregnancy outcomes; however, the infection is difficult to control because the nonspecific clinical manifestations and rarity of the disease often preclude early diagnosis. We encountered 2 cases of pregnancy-associated listeriosis that occurred at 29 and 37 weeks of gestation. Both neonates were delivered by emergent cesarean section due to fetal condition, and one of the preterm infants died immediately after birth. Pregnancy-associated listeriosis should be considered in the management of unexplained fever or inflammatory conditions in pregnant women.

摘要

李斯特菌病是一种由……引起的罕见食源性感染。与普通人群相比,孕妇中的发病率高12至20倍,新生儿死亡率为20%至40%。早期使用适当的抗菌药物治疗对妊娠结局至关重要;然而,由于该疾病的非特异性临床表现和罕见性,常常难以早期诊断,因此感染难以控制。我们遇到了2例妊娠相关李斯特菌病病例,分别发生在妊娠29周和37周。由于胎儿状况,两名新生儿均通过紧急剖宫产分娩,其中一名早产儿出生后立即死亡。在处理孕妇不明原因发热或炎症性疾病时,应考虑妊娠相关李斯特菌病。

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