Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
Am J Ind Med. 2019 Jan;62(1):80-84. doi: 10.1002/ajim.22921. Epub 2018 Nov 25.
We describe four cases of slaughterhouse workers with occupational immediate allergy to raw pork allergens, confirmed by positive skin prick testing and specific immunoglobulin E (IgE) antibodies. Our first patient was diagnosed with occupational asthma from raw pork allergens. Two patients were diagnosed with occupational rhinitis caused by raw pork allergens, which was confirmed by a nasal provocation test. One of these also had occupational contact urticaria caused by raw pork meat. We were unable to diagnose an occupational respiratory or skin disease in the fourth patient, despite signs of immediate sensitization to raw pork meat from occupational exposure. Based on proper diagnoses, measures to prevent allergen exposure were taken, which led to the improvement of symptoms in these four patients. The present patient cases highlight the importance of recognition of early signs of occupational allergy and identification of causative allergens in order to allow avoidance of allergens, with the aim of preventing persistence and worsening of symptoms.
我们描述了 4 例屠宰场工人因职业性即刻过敏而对生猪肉过敏原过敏的病例，这些病例通过皮试和特异性免疫球蛋白 E（IgE）抗体检测得到了证实。我们的第一位患者被诊断为职业性哮喘，由生猪肉过敏原引起。两名患者被诊断为职业性鼻炎，由生猪肉过敏原引起，这通过鼻激发试验得到了证实。其中一名患者还患有职业性接触性荨麻疹，由生猪肉引起。我们未能在第四位患者中诊断出职业性呼吸道或皮肤疾病，尽管他有因职业接触生猪肉而出现即刻过敏的迹象。基于正确的诊断，采取了防止过敏原暴露的措施，这导致了这四位患者症状的改善。本病例强调了识别职业性过敏早期迹象和识别致病过敏原的重要性，以便避免接触过敏原，从而预防症状的持续和恶化。
