Tulipan N
Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Neurol Clin. 1988 May;6(2):405-20.
There is now a wealth of experimental evidence to suggest that transplantation to the brain may ameliorate a variety of neurologic and endocrine disorders. Many unanswered questions remain. Chief among these questions are the duration of any salutary effects and the potential long-term risks to the host CNS. Answers to these questions will only come with carefully controlled long-term clinical studies. Given the high incidence and devastating nature of many of these diseases, such studies will have enormous scientific and social impact. Regardless of the outcome, there is the potential for a greater understanding of the pathologic mechanisms underlying neurodegenerative diseases and, thus, the possibility that definitive therapies will be found as a result.
现在有大量实验证据表明，移植到大脑可能改善多种神经和内分泌疾病。许多问题仍未得到解答。这些问题中最主要的是任何有益效果的持续时间以及对宿主中枢神经系统的潜在长期风险。只有通过精心控制的长期临床研究才能找到这些问题的答案。鉴于这些疾病中许多疾病的高发病率和破坏性本质，此类研究将产生巨大的科学和社会影响。无论结果如何，都有可能更深入地了解神经退行性疾病的病理机制，从而有可能找到确切的治疗方法。
