Schwarz O, Dormont D, Lesser J, Andrieu J M
Division de Radiologie et Radioprotection, Centre de Recherches du Service de Santé des Armées, Clamart, France.
Nouv Rev Fr Hematol (1978). 1988;30(3):183-9.
The Sternberg cell, the malignant cell of Hodgkin's disease, remains of uncertain nature 80 years after it was first described. Numerous hypotheses have been advanced as to its origin: that it derives from the macrophages, B lymphocyte, T lymphocyte, interdigitating reticulum cell or even from an as yet unidentified cell-line. We here review these various hypotheses, as well as the different techniques used for its study. The morphologic, ultrastructural, histochemical and immunologic studies are discussed in detail.
施特恩贝格细胞是霍奇金病的恶性细胞，自首次被描述以来80年，其性质仍不确定。关于其起源已提出众多假说：它源自巨噬细胞、B淋巴细胞、T淋巴细胞、交错突网状细胞，甚至源自一种尚未明确的细胞系。我们在此回顾这些不同的假说，以及用于研究它的不同技术。详细讨论了形态学、超微结构、组织化学和免疫学研究。
