Women's Health Development Unit, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia; Department of Pharmacology, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Cheras, 56000, Kuala Lumpur, Malaysia.
Women's Health Development Unit, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
Complement Ther Med. 2018 Dec;41:154-160. doi: 10.1016/j.ctim.2018.08.015. Epub 2018 Sep 5.
To investigate the long-term effects of Tualang Honey versus Honey Cocktail (mixture of honey, bee bread, and royal jelly) on cardiovascular markers and anthropometric measurements of postmenopausal women.
We conducted a randomised, double blinded, two-armed parallel study comparing 20 g/day of Tualang Honey versus 20 g/day Honey Cocktail among postmenopausal women aged 45-65 years. The cardiovascular parameters and anthropometrics measurements were assessed at baseline, 6 months, and 12 months of the intervention.
100 subjects were successfully randomised into the groups. There was a significant decrease in the diastolic blood pressure from 77.92 mmHg at baseline to 73.45 mmHg at 12 months (F-statistic = 2.55, p-value = 0.047) in the Tualang Honey group compared to Honey Cocktail. There was also a significant decrease in the fasting blood sugar from 6.11 mmol/L at baseline to 5.71 mmol/L at 12 months (F-statistic = 4.03, p-value = 0.021) in the Tualang Honey group compared to the Honey Cocktail group. The body mass index remained unchanged at 27 kg/m2 (F-statistic = 1.60, p-value = 0.010) throughout 12 months of the intervention in the Honey Cocktail group.
Subjects who received Honey Cocktail showed remarkable effects on body mass index. However, Tualang Honey supplementation showed superior effect in lowering diastolic blood pressure and fasting blood sugar compared to Honey Cocktail. Further studies are required to ascertain the underlying mechanism(s) of Tualang Honey and Honey Cocktail on each observed parameter.
研究塔兰蜂蜜与蜂蜜鸡尾酒(蜂蜜、蜂粮和蜂王浆的混合物)对绝经后女性心血管标志物和人体测量学指标的长期影响。
我们进行了一项随机、双盲、双臂平行研究,比较了 20g/天的塔兰蜂蜜与 20g/天的蜂蜜鸡尾酒在 45-65 岁绝经后女性中的应用。在干预的基线、6 个月和 12 个月时评估心血管参数和人体测量学测量值。
100 名受试者成功随机分为两组。与蜂蜜鸡尾酒组相比,塔兰蜂蜜组的舒张压从基线时的 77.92mmHg 显著下降至 12 个月时的 73.45mmHg(F 统计量=2.55,p 值=0.047)。与蜂蜜鸡尾酒组相比,塔兰蜂蜜组的空腹血糖也从基线时的 6.11mmol/L 显著下降至 12 个月时的 5.71mmol/L(F 统计量=4.03,p 值=0.021)。在整个 12 个月的干预期间,蜂蜜鸡尾酒组的体重指数保持在 27kg/m2 不变(F 统计量=1.60,p 值=0.010)。
接受蜂蜜鸡尾酒的受试者在体重指数方面表现出显著的效果。然而,与蜂蜜鸡尾酒相比,塔兰蜂蜜补充剂在降低舒张压和空腹血糖方面表现出更好的效果。需要进一步的研究来确定塔兰蜂蜜和蜂蜜鸡尾酒对每个观察到的参数的潜在机制。