Ringenberg Q S, Doll D C, Patterson W P, Perry M C, Yarbro J W
Medical Service, Harry S. Truman Memorial Veterans Hospital, Columbia, Mo.
South Med J. 1988 Sep;81(9):1132-9. doi: 10.1097/00007611-198809000-00016.
Heavy metal poisoning can cause a variety of hematologic disorders. Exposure to heavy metals is ubiquitous in the industrial environment and must be considered in the differential diagnosis of many types of anemia. The heavy metals most commonly associated with hematologic toxicity are arsenic and its derivative arsine, copper, gold, lead, and zinc. A few distinctive clinical features characterize the hematologic manifestations of many occult heavy metal poisonings. These features have a limited differential diagnosis. A knowledge of these clinical features can assist the astute clinician in making the correct diagnosis.
重金属中毒可导致多种血液系统疾病。在工业环境中，接触重金属的情况普遍存在，在多种类型贫血的鉴别诊断中必须予以考虑。最常与血液毒性相关的重金属是砷及其衍生物胂、铜、金、铅和锌。许多隐匿性重金属中毒的血液学表现具有一些独特的临床特征。这些特征的鉴别诊断范围有限。了解这些临床特征有助于敏锐的临床医生做出正确诊断。
