Ordóñez N G, Sneige N, Hickey R C, Brooks T E
Department of Pathology, University of Texas M. D. Anderson Hospital and Tumor Institute, Houston.
Acta Cytol. 1988 Sep-Oct;32(5):684-8.
The value of mouse monoclonal antibody (MAb) HMB-45 for the diagnosis of melanoma was retrospectively evaluated in cytologic preparations. Twenty-two (68.7%) of the 32 melanoma cases studied reacted with MAb HMB-45 while none of the 36 nonmelanoma tumors stained with this antibody. These results indicate that MAb HMB-45 can be helpful in the diagnosis of melanoma, especially in those patients who have no clinical indications of having a metastatic melanoma or in some cases in which the presence of melanin cannot be demonstrated by special histochemical stains.
