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使用多脉冲掺铒钇铝石榴石激光联合空间调制消融(SMA)模块治疗膨胀纹的临床疗效:一项针对20例患者的前瞻性初步研究。

Clinical benefit of using a multifractional Er:YAG laser combined with a spatially modulated ablative (SMA) module for the treatment of striae distensae: A prospective pilot study in 20 patients.

作者信息

Meningaud Jean Paul, SidAhmed-Mezi Mounia, Billon Raphaelle, Rem Kessara, La Padula Simone, Hersant Barbara

机构信息

Department of Plastic, Reconstructive and Maxillo facial Surgery, Hopital Henri Mondor, Creteil, 94010, France.

出版信息

Lasers Surg Med. 2019 Mar;51(3):230-238. doi: 10.1002/lsm.23042. Epub 2018 Nov 27.

Abstract

BACKGROUND AND OBJECTIVE

Striae distensae (SD) are cutaneous lesions that often occur on the breasts, abdomen, hips, and thighs. The aim of this study is to evaluate the effectiveness of a new technique using a non-invasive Er:YAG laser combined with Spatially Modulated Ablation (SMA) module for the treatment of SD.

STUDY DESIGN/MATERIALS AND METHODS: This prospective pilot clinical study included 20 patients with skin phototypes I to IV who are affected by SD. The Er:YAG 2940 nm laser with SMA module was used in scanning mode with fluences of 2.3 J/cm , frequency of 3 Hz, and pulse duration of 0.3 milliseconds. The laser beam is split into several microspots and penetrates only by 50 μm in the epidermis thickness. This technology induces also the generation of acoustic waves to stimulate tissue regeneration. Each patient underwent six laser sessions. An objective and subjective assessment of SD were used. All adverse events were reported.

RESULTS

Most patients reported good improvement and expressed their satisfaction with the treatment. Cutometric analysis showed significant improvement in skin elasticity at the end of study. Moreover, ultrasound analysis revealed an increase in dermal thickness (P < 0.01). POSAS scores decreased significantly at 3 and 6 months, reflecting improved skin quality. The average recovery time was 5 days, with no adverse effects reported.

CONCLUSION

Using Er:YAG laser (2,940 nm) with SMA technology to treat SD resulted in improved volume and textural appearance without side effects. The elasticity and thickness of the dermis also improved. The Er:YAG laser with SMA module may be considered as a novel and effective technique to treat SD lesions with minimal time recovery. Lasers Surg. Med. 51:230-238, 2019. © 2018 Wiley Periodicals, Inc.

摘要

背景与目的

膨胀纹(SD)是一种常见于乳房、腹部、臀部和大腿的皮肤病变。本研究旨在评估一种结合非侵入性铒钇铝石榴石(Er:YAG)激光与空间调制消融(SMA)模块的新技术治疗膨胀纹的有效性。

研究设计/材料与方法:这项前瞻性试点临床研究纳入了20例皮肤光型为I至IV型且患有膨胀纹的患者。采用带有SMA模块的2940 nm Er:YAG激光,以扫描模式进行治疗,能量密度为2.3 J/cm²,频率为3 Hz,脉冲持续时间为0.3毫秒。激光束被分成多个微光斑,仅穿透表皮厚度50μm。该技术还能诱导声波产生以刺激组织再生。每位患者接受6次激光治疗。对膨胀纹进行了客观和主观评估,并报告了所有不良事件。

结果

大多数患者报告病情有明显改善,并对治疗表示满意。皮肤测量分析显示,研究结束时皮肤弹性有显著改善。此外,超声分析显示真皮厚度增加(P < 0.01)。POSAS评分在3个月和6个月时显著降低,反映出皮肤质量有所改善。平均恢复时间为5天,未报告有不良反应。

结论

使用带有SMA技术的Er:YAG激光(2940 nm)治疗膨胀纹可改善体积和质地外观,且无副作用。真皮的弹性和厚度也有所改善。带有SMA模块的Er:YAG激光可被视为一种新颖有效的技术,能以最短的恢复时间治疗膨胀纹病变。《激光外科与医学》2019年第51卷:230 - 238页。© 2018威利期刊公司

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