Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany.
Institute for Integrative Medicine, Department of Health, Witten/Herdecke University, Herdecke, Germany.
BMC Complement Altern Med. 2018 Nov 27;18(1):311. doi: 10.1186/s12906-018-2369-4.
Neural Therapy (NT) is a common complementary treatment approach using injections with short-acting local anesthetics to treat pain and chronic diseases. However, little is known about the underlying mechanisms and the domains of treatment response. This study therefore analyzed patient experiences following NT injections with procaine.
Maximum variation sampling was used to collect data from semi-structured interviews conducted with 22 hospital inpatients aged 59.6 ± 14.9 years (81.8% female). Each had multiple (9.4 ± 6.9) diagnoses. They were undergoing two weeks of integrative treatment, which included individualized NT. The interview data were analyzed in MAXQDA using qualitative content analysis.
With injection, patients first described local anesthetic effects including temporary blocking of pain and increased local warmth. Second, patients reported on vegetative reactions frequently leading to turmoil within the body like initial aggravation of existing symptoms or the appearance of new, concealed or phantom symptoms. This often required the need for rest to deal with the treatment stimulus. As a third step, many patients could gain physical and emotional release and relief in symptoms, mood and functioning. Emotional release was often accompanied by weeping and initially overwhelmed affected patients with dissociated memories. However, in cases where patients were able to experience those memories with a new distance, a fourth step of integration was achievable. It included reframing processes as well as a gain in pain perception and body-awareness. As a possible fifth step, patients experienced improved mood, increased pain acceptance and empowerment. Adverse events of NT included pain from the injections, vegetative complaints and emotional turmoil that lasted for minutes or hours, with a maximum of two days.
Patients treated with procaine injections reported different psychophysiological outcomes contributing to the understanding of the mechanisms underlying NT. Further efficacy studies should separate specific NT from non-specific/placebo effects.
DRKS00004567 .
神经疗法（NT）是一种常见的补充治疗方法，使用短效局部麻醉剂注射来治疗疼痛和慢性疾病。然而，对于其潜在机制和治疗反应的领域知之甚少。因此，本研究分析了使用普鲁卡因进行 NT 注射后的患者体验。
使用最大变异抽样从 22 名年龄为 59.6±14.9 岁（81.8%为女性）的住院患者的半结构式访谈中收集数据。每位患者都有多个（9.4±6.9）诊断。他们正在接受为期两周的综合治疗，其中包括个体化 NT。使用 MAXQDA 对访谈数据进行定性内容分析。
在注射时，患者首先描述了局部麻醉剂的作用，包括暂时阻断疼痛和增加局部温暖感。其次，患者报告了经常导致体内动荡的植物性反应，例如现有症状的最初加重或新的、隐藏的或幻影症状的出现。这通常需要休息来应对治疗刺激。第三步，许多患者可以在症状、情绪和功能方面获得身体和情感的释放和缓解。情感释放通常伴随着哭泣，最初使受影响的患者感到分离的记忆。然而，在患者能够以新的距离体验这些记忆的情况下，就可以实现第四步整合。它包括重新构建过程以及疼痛感知和身体意识的增强。作为可能的第五步，患者体验到情绪改善、增加的疼痛耐受和赋权。NT 的不良反应包括注射引起的疼痛、植物性投诉和情绪波动，持续数分钟或数小时，最长可达两天。
接受普鲁卡因注射治疗的患者报告了不同的身心结果，有助于理解 NT 的潜在机制。进一步的疗效研究应将特定的 NT 与非特异性/安慰剂效应分开。
DRKS00004567。
