由胰岛淀粉样蛋白的一个片段形成的淀粉样纤维。
Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein.
作者信息
Glenner G G, Eanes E D, Wiley C A
机构信息
University of California, San Diego, La Jolla 92093.
出版信息
Biochem Biophys Res Commun. 1988 Sep 15;155(2):608-14. doi: 10.1016/s0006-291x(88)80538-2.
PMID:3048259
Abstract
A synthetic peptide formed from residues 20-29 of the pancreatic islet amyloid protein has the confirmation of a twisted beta-pleated sheet protein suggesting it is a potential contributor toward amyloid fibril formation in the islets of Langerhans in Type 2 diabetes mellitus.
摘要
一种由胰岛淀粉样蛋白20 - 29位残基形成的合成肽具有扭曲的β-折叠片层蛋白构象，这表明它可能是2型糖尿病患者胰岛中淀粉样纤维形成的一个潜在因素。
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