• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

中国城市中年轻女性宫颈癌死亡率上升。

Rising Mortality Rate of Cervical Cancer in Younger Women in Urban China.

机构信息

Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.

Department of Preventive Medicine, School of Health Sciences, Wuhan University, Wuhan, 430071, China.

出版信息

J Gen Intern Med. 2019 Feb;34(2):281-284. doi: 10.1007/s11606-018-4732-z. Epub 2018 Nov 27.

DOI:10.1007/s11606-018-4732-z
PMID:30484099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6374275/
Abstract

BACKGROUND

In recent decades, much effort has been made in China to reduce the burden of cervical cancer.

OBJECTIVE

Our study's purpose was to examine trends of cervical cancer mortality in each 5-year age group for urban and rural Chinese women, respectively.

DESIGNS

Retrospective analysis of cervical cancer mortality from 1987 to 2015 from the World Health Organization Cancer Mortality Database and China Health Statistical Yearbooks.

PARTICIPANTS

Chinese women.

MAIN MEASURES

Trends were examined using annual percent change (APC) and average annual percent change (AAPC) via Joinpoint regression models for each 5-year age group in urban and rural areas, respectively.

RESULTS

In urban China, mortality rate of cervical cancer increased significantly among urban women aged 25-54 years (AAPC 2.125.49%), in contrast to a decline trend among urban women older than 60 years (AAPC - 3.61- 5.35%). In rural China, cervical cancer rates declined in all age groups, but the magnitude was smaller in women aged 30-54 years (AAPC - 0.59- 2.20%) compared to women older than 55 years (AAPC - 3.06- 4.33%).

CONCLUSION

Mortality rate of cervical cancer is rising at an alarming rate in younger women in urban China. Timely intervention is required for these vulnerable populations.

摘要

背景

近几十年来,中国在降低宫颈癌负担方面做出了巨大努力。

目的

本研究旨在分别研究城市和农村中国女性各 5 岁年龄组宫颈癌死亡率的趋势。

设计

回顾性分析 1987 年至 2015 年世界卫生组织癌症死亡率数据库和中国卫生统计年鉴中宫颈癌死亡率的数据。

参与者

中国女性。

主要措施

分别采用 Joinpoint 回归模型,通过每年百分比变化(APC)和平均每年百分比变化(AAPC),对城市和农村地区每个 5 岁年龄组的趋势进行了检查。

结果

在城市地区,25-54 岁的城市妇女的宫颈癌死亡率显著上升(APC 2.125.49%),而 60 岁以上的城市妇女死亡率呈下降趋势(APC -3.61-5.35%)。在农村地区,所有年龄组的宫颈癌发病率均呈下降趋势,但 30-54 岁妇女的下降幅度(APC -0.59-2.20%)小于 55 岁以上妇女(APC -3.06-4.33%)。

结论

城市地区年轻女性宫颈癌死亡率呈上升趋势,令人担忧。需要对这些弱势群体进行及时干预。

相似文献

1
Rising Mortality Rate of Cervical Cancer in Younger Women in Urban China.中国城市中年轻女性宫颈癌死亡率上升。
J Gen Intern Med. 2019 Feb;34(2):281-284. doi: 10.1007/s11606-018-4732-z. Epub 2018 Nov 27.
2
National age-specific mortality trends for cervical and breast cancers in urban-rural areas of China from 2009 to 2021: a population-based analysis.2009 年至 2021 年中国城乡地区宫颈癌和乳腺癌的年龄别死亡率趋势:基于人群的分析。
Mil Med Res. 2024 Aug 13;11(1):55. doi: 10.1186/s40779-024-00561-4.
3
[Disease burden of colorectal cancer in China: any changes in recent years?].[中国结直肠癌的疾病负担:近年来有何变化?]
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Oct 10;41(10):1633-1642. doi: 10.3760/cma.j.cn112338-20200306-00273.
4
Comparison of Secular Trends in Cervical Cancer Mortality in China and the United States: An Age-Period-Cohort Analysis.中国和美国宫颈癌死亡率的长期趋势比较:年龄-时期-队列分析
Int J Environ Res Public Health. 2016 Nov 17;13(11):1148. doi: 10.3390/ijerph13111148.
5
[Analysis on mortality of cervical cancer and its temporal trend in women in China, 2006-2012].[2006 - 2012年中国女性宫颈癌死亡率及其时间趋势分析]
Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Jan 10;38(1):58-64. doi: 10.3760/cma.j.issn.0254-6450.2017.01.011.
6
[Trend analysis of cervical cancer incidence and mortality rates in Chinese women during 1989-2008].1989 - 2008年中国女性宫颈癌发病率与死亡率的趋势分析
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2014 Apr;36(2):119-25. doi: 10.3881/j.issn.1000-503X.2014.02.001.
7
Long-term trends of liver cancer mortality by gender in urban and rural areas in China: an age-period-cohort analysis.中国城乡地区肝癌死亡率的长期性别趋势:年龄-时期-队列分析
BMJ Open. 2018 Feb 8;8(2):e020490. doi: 10.1136/bmjopen-2017-020490.
8
Cervical Cancer Mortality Trends in China, 1991-2013, and Predictions for the Future.1991 - 2013年中国宫颈癌死亡率趋势及未来预测
Asian Pac J Cancer Prev. 2015;16(15):6391-6. doi: 10.7314/apjcp.2015.16.15.6391.
9
The trends of mortality and years of life lost of cancers in urban and rural areas in China, 1990-2017.中国城乡地区 1990-2017 年癌症死亡率和寿命损失年趋势。
Cancer Med. 2020 Feb;9(4):1562-1571. doi: 10.1002/cam4.2765. Epub 2019 Dec 24.
10
[Mortality trend in nasopharynx cancer in Chinese resident from 1987 to 2015].1987年至2015年中国居民鼻咽癌死亡率趋势
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Jul 28;43(7):760-766. doi: 10.11817/j.issn.1672-7347.2018.07.010.

引用本文的文献

1
ADAMDEC1 promotes cervical squamous cell carcinoma by enhancing the JAK/STAT signaling pathway through modulation of TYMP.ADAMDEC1通过调节TYMP增强JAK/STAT信号通路来促进宫颈鳞状细胞癌。
Naunyn Schmiedebergs Arch Pharmacol. 2025 May;398(5):6009-6020. doi: 10.1007/s00210-024-03680-w. Epub 2024 Dec 3.
2
The role of circular RNA targeting IGF2BPs in cancer-a potential target for cancer therapy.环状 RNA 靶向 IGF2BPs 在癌症中的作用——癌症治疗的潜在靶点。
J Mol Med (Berl). 2024 Nov;102(11):1297-1314. doi: 10.1007/s00109-024-02488-8. Epub 2024 Sep 17.
3
Integrating Single-Cell RNA-Seq and Bulk RNA-Seq to Construct a Novel γδT Cell-Related Prognostic Signature for Human Papillomavirus-Infected Cervical Cancer.整合单细胞 RNA-Seq 和批量 RNA-Seq 构建新型人乳头瘤病毒感染宫颈癌 γδT 细胞相关预后标志物。
Cancer Control. 2024 Jan-Dec;31:10732748241274228. doi: 10.1177/10732748241274228.
4
Human papilloma virus (HPV)-related information acquisition and seeking behavior among infected women: A single center cross-sectional survey in Shanghai, China.中国上海某单中心横断面调查:感染女性人乳头瘤病毒(HPV)相关信息获取及需求行为研究
Glob Health Med. 2024 Jun 30;6(3):212-217. doi: 10.35772/ghm.2023.01100.
5
Decoding Fujian's cervical HPV landscape: unmasking dominance of non-16/18 HR-HPV and tailoring prevention strategies at a large scale.解码福建的宫颈 HPV 景观:揭示非 16/18 型 HR-HPV 的主导地位,并在大规模水平上制定预防策略。
Front Public Health. 2024 Jun 6;12:1357073. doi: 10.3389/fpubh.2024.1357073. eCollection 2024.
6
Human Papilloma Virus Infection and Gene Subtypes Analysis in Women Undergoing Physical Examinations: A 2015-2020 Study in Wenzhou, China.人乳头瘤病毒感染与基因亚型分析在接受体检的女性:2015-2020 年在中国温州的研究。
Cancer Control. 2024 Jan-Dec;31:10732748241257902. doi: 10.1177/10732748241257902.
7
The Landscape of Health Technology for Equity Deserving Groups in Rural Communities: A Systematic Review.农村社区公平应得群体的卫生技术状况:一项系统综述
Community Health Equity Res Policy. 2025 Apr;45(3):315-335. doi: 10.1177/2752535X241252208. Epub 2024 May 7.
8
MUC1 promotes cervical squamous cell carcinoma through ERK phosphorylation-mediated regulation of ITGA2/ITGA3.MUC1通过ERK磷酸化介导的ITGA2/ITGA3调节促进宫颈鳞状细胞癌。
BMC Cancer. 2024 May 3;24(1):559. doi: 10.1186/s12885-024-12314-6.
9
Analysis of influencing factors of HPV vaccination willingness of female sex workers in urban entertainment venues based on the IMB model in Guangxi, China.基于广西城市娱乐场所性工作者 HPV 疫苗接种意愿的 IMB 模型的影响因素分析。
BMC Womens Health. 2024 Feb 24;24(1):141. doi: 10.1186/s12905-024-02962-y.
10
Comparative cost-effectiveness of first-line pembrolizumab plus chemotherapy vs. chemotherapy alone in persistent, recurrent, or metastatic cervical cancer.一线帕博利珠单抗联合化疗与单纯化疗治疗持续性、复发性或转移性宫颈癌的成本效益比较。
Front Immunol. 2024 Jan 11;14:1345942. doi: 10.3389/fimmu.2023.1345942. eCollection 2023.

本文引用的文献

1
Different trends in colorectal cancer mortality between age groups in China: an age-period-cohort and joinpoint analysis.中国不同年龄组结直肠癌死亡率的变化趋势:基于年龄-时期-队列和联合分析
Public Health. 2019 Jan;166:45-52. doi: 10.1016/j.puhe.2018.08.007. Epub 2018 Nov 15.
2
Parental acceptability of HPV vaccination for boys and girls aged 9-13 years in China - A population-based study.家长对 9-13 岁男童和女童接种 HPV 疫苗的可接受性 - 一项基于人群的研究。
Vaccine. 2018 May 3;36(19):2657-2665. doi: 10.1016/j.vaccine.2018.03.057. Epub 2018 Mar 30.
3
Evaluation on the persistence of anti-HPV immune responses to the quadrivalent HPV vaccine in Chinese females and males: Up to 3.5 years of follow-up.评价四价 HPV 疫苗在中国女性和男性中针对 HPV 免疫应答的持久性:长达 3.5 年的随访。
Vaccine. 2018 Mar 7;36(11):1368-1374. doi: 10.1016/j.vaccine.2018.02.006. Epub 2018 Feb 7.
4
Human papillomavirus viral load as a useful triage tool for non-16/18 high-risk human papillomavirus positive women: A prospective screening cohort study.人乳头瘤病毒病毒载量作为非 16/18 高危型人乳头瘤病毒阳性妇女的有用分诊工具:一项前瞻性筛查队列研究。
Gynecol Oncol. 2018 Jan;148(1):103-110. doi: 10.1016/j.ygyno.2017.11.016. Epub 2017 Nov 21.
5
Cancer incidence and mortality among young adults aged 20-39 years worldwide in 2012: a population-based study.2012 年全球 20-39 岁年轻人癌症发病率和死亡率:一项基于人群的研究。
Lancet Oncol. 2017 Dec;18(12):1579-1589. doi: 10.1016/S1470-2045(17)30677-0. Epub 2017 Oct 27.
6
Correlation analysis between the parameters of contrast-enhanced ultrasonography in evaluating cervical cancer metastasis and expression of E-cadherin.超声造影评估宫颈癌转移参数与E-钙黏蛋白表达的相关性分析
Oncol Lett. 2017 Oct;14(4):4641-4646. doi: 10.3892/ol.2017.6785. Epub 2017 Aug 22.
7
Cervical cancer histology image identification method based on texture and lesion area features.基于纹理和病变区域特征的宫颈癌组织学图像识别方法。
Comput Assist Surg (Abingdon). 2017 Dec;22(sup1):186-199. doi: 10.1080/24699322.2017.1389397. Epub 2017 Oct 16.
8
Multimodal treatment including hysterectomy improves survival in patients with locally advanced cervical cancer: A population-based, propensity score-matched analysis.多模态治疗包括子宫切除术可改善局部晚期宫颈癌患者的生存:一项基于人群的倾向评分匹配分析。
Int J Surg. 2017 Dec;48:122-127. doi: 10.1016/j.ijsu.2017.10.028. Epub 2017 Oct 12.
9
Evaluation of short- and long-term efficacy of chemoradiotherapy for advanced cervical cancer using HSP70 protein combined with multimodal MRI.采用 HSP70 蛋白联合多模态 MRI 评价中晚期宫颈癌放化疗的近期及远期疗效。
J Cell Biochem. 2018 Apr;119(4):3017-3029. doi: 10.1002/jcb.26424. Epub 2017 Dec 29.
10
Short- and long-term outcomes of laparoscopic radical hysterectomy for obese patients with cervical cancer.肥胖宫颈癌患者腹腔镜根治性子宫切除术的短期和长期结局
J BUON. 2017 Jul-Aug;22(4):958-965.