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中国城市中年轻女性宫颈癌死亡率上升。

Rising Mortality Rate of Cervical Cancer in Younger Women in Urban China.

机构信息

Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.

Department of Preventive Medicine, School of Health Sciences, Wuhan University, Wuhan, 430071, China.

出版信息

J Gen Intern Med. 2019 Feb;34(2):281-284. doi: 10.1007/s11606-018-4732-z. Epub 2018 Nov 27.

Abstract

BACKGROUND

In recent decades, much effort has been made in China to reduce the burden of cervical cancer.

OBJECTIVE

Our study's purpose was to examine trends of cervical cancer mortality in each 5-year age group for urban and rural Chinese women, respectively.

DESIGNS

Retrospective analysis of cervical cancer mortality from 1987 to 2015 from the World Health Organization Cancer Mortality Database and China Health Statistical Yearbooks.

PARTICIPANTS

Chinese women.

MAIN MEASURES

Trends were examined using annual percent change (APC) and average annual percent change (AAPC) via Joinpoint regression models for each 5-year age group in urban and rural areas, respectively.

RESULTS

In urban China, mortality rate of cervical cancer increased significantly among urban women aged 25-54 years (AAPC 2.125.49%), in contrast to a decline trend among urban women older than 60 years (AAPC - 3.61- 5.35%). In rural China, cervical cancer rates declined in all age groups, but the magnitude was smaller in women aged 30-54 years (AAPC - 0.59- 2.20%) compared to women older than 55 years (AAPC - 3.06- 4.33%).

CONCLUSION

Mortality rate of cervical cancer is rising at an alarming rate in younger women in urban China. Timely intervention is required for these vulnerable populations.

摘要

背景

近几十年来,中国在降低宫颈癌负担方面做出了巨大努力。

目的

本研究旨在分别研究城市和农村中国女性各 5 岁年龄组宫颈癌死亡率的趋势。

设计

回顾性分析 1987 年至 2015 年世界卫生组织癌症死亡率数据库和中国卫生统计年鉴中宫颈癌死亡率的数据。

参与者

中国女性。

主要措施

分别采用 Joinpoint 回归模型,通过每年百分比变化(APC)和平均每年百分比变化(AAPC),对城市和农村地区每个 5 岁年龄组的趋势进行了检查。

结果

在城市地区,25-54 岁的城市妇女的宫颈癌死亡率显著上升(APC 2.125.49%),而 60 岁以上的城市妇女死亡率呈下降趋势(APC -3.61-5.35%)。在农村地区,所有年龄组的宫颈癌发病率均呈下降趋势,但 30-54 岁妇女的下降幅度(APC -0.59-2.20%)小于 55 岁以上妇女(APC -3.06-4.33%)。

结论

城市地区年轻女性宫颈癌死亡率呈上升趋势,令人担忧。需要对这些弱势群体进行及时干预。

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Rising Mortality Rate of Cervical Cancer in Younger Women in Urban China.中国城市中年轻女性宫颈癌死亡率上升。
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