Doumbo Safiatou Niaré, Ongoïba Aissata, Doumtabe Didier, Tran Tuan M, Traoré Abdrahamane, Sangala Jules, Kayentao Kassoum, Compton Peter D, Traoré Boubacar, Doumbo Ogobara K
Mali Med. 2018;33(1):10-15.
Soil transmitted helminthiasis and schistosomiasis are neglected tropical diseases (NTD), affecting the health status of endemic Malian populations. Mali has a national NTD elimination program using the mass drug administration (MDA) strategy combining Albendazole, Ivermectinand Praziquantel. Malaria still remains a public health problem in Mali. The Community health Center (CSCOM) in Kalifabougouvillage in the Kati health district has benefited from such MDA program since 2010.
To evaluate the prevalence rate of malaria, intestinal and urinary parasite infections in the local population.
We conducted a nested cross sectional and cohort study in May 2011 on volunteers aged three months old to 25 years old. Blood smear (blood), Kato-Katz (Stools) and urine filtration techniques were used to evaluate parasite prevalence. Informed consent and assentment were obtained from the volunteers before their inclusion. All volunteers received treatment against the parasite diseases of interest according to the guidelines of national disease control programs.
A total of 688 volunteers were included. The prevalence rates of parasitic infections were 22.1% [95% CI= 22.06 - 22.12] for , 9% [95% CI: 8.9-9.034] for ; 3.5% [95% CI: 3.48-3.513] for and 0.1% [95% CI : 0.093-0.107] for . The prevalence rate of the co-infection was 2.18% [95% CI= 2.17 - 2.19] in Kalifabougou.
Praziquantel and Albendazole-based MDA and Artemisinin based combined therapy (ACTs) could explain theobserved low prevalence of helminthiasis and malaria in Kalifabougou, Mali.
土壤传播的蠕虫病和血吸虫病是被忽视的热带病（NTD），影响着马里流行地区人群的健康状况。马里有一项国家消除被忽视热带病计划，采用大规模药物管理（MDA）策略，联合使用阿苯达唑、伊维菌素和吡喹酮。疟疾在马里仍然是一个公共卫生问题。自2010年以来，卡蒂健康区卡里法布古村的社区卫生中心（CSCOM）受益于此类大规模药物管理计划。
评估当地人群中疟疾、肠道和泌尿寄生虫感染的患病率。
2011年5月，我们对3个月至25岁的志愿者进行了一项嵌套横断面和队列研究。采用血涂片（血液）、加藤厚涂片（粪便）和尿液过滤技术评估寄生虫患病率。在纳入志愿者之前，获得了他们的知情同意和同意。所有志愿者均根据国家疾病控制计划的指南接受针对相关寄生虫病的治疗。
共纳入688名志愿者。寄生虫感染的患病率分别为：[具体寄生虫1]为22.1% [95%置信区间= 22.06 - 22.12]，[具体寄生虫2]为9% [95%置信区间：8.9 - 9.034]；[具体寄生虫3]为3.5% [95%置信区间：3.48 - 3.513]，[具体寄生虫4]为0.1% [95%置信区间：0.093 - 0.107]。在卡里法布古，混合感染[具体混合感染情况]的患病率为2.18% [95%置信区间= 2.17 - 2.19]。
基于吡喹酮和阿苯达唑的大规模药物管理以及基于青蒿素的联合疗法（ACTs）可以解释在马里卡里法布古观察到的蠕虫病和疟疾低患病率。
