Mempin Maria, Hu Honghua, Chowdhury Durdana, Deva Anand, Vickery Karen
Faculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia.
Materials (Basel). 2018 Nov 28;11(12):2393. doi: 10.3390/ma11122393.
Breast implantation either for cosmetic or reconstructive e purposes is one of the most common procedures performed in plastic surgery. Biofilm infection is hypothesised to be involved in the development of both capsular contracture and anaplastic large cell lymphoma (ALCL). Capsular contracture is one of the principal reasons for breast revision surgery and is characterised by the tightening and hardening of the capsule surrounding the implant, and ALCL is an indolent lymphoma found only in women with textured implants. We describe the types of breast implants available with regard to their surface characteristics of surface area and roughness and how this might contribute to capsular contracture and/or biofilm formation. The pathogenesis of capsular contracture is thought to be due to biofilm formation on the implant, which results in on-going inflammation. We describe the current research into breast implant associated ALCL and how implant properties may affect its pathogenesis, with ALCL only occurring in women with textured implants.
乳房植入术无论是用于美容还是重建目的,都是整形外科中最常见的手术之一。生物膜感染被认为与包膜挛缩和间变性大细胞淋巴瘤(ALCL)的发生有关。包膜挛缩是乳房修复手术的主要原因之一,其特征是植入物周围的包膜收紧和硬化,而ALCL是一种仅在使用表面有纹理的植入物的女性中发现的惰性淋巴瘤。我们描述了现有乳房植入物的类型及其表面积和粗糙度等表面特征,以及这可能如何导致包膜挛缩和/或生物膜形成。包膜挛缩的发病机制被认为是由于植入物上形成生物膜,从而导致持续的炎症。我们描述了目前对乳房植入物相关ALCL的研究,以及植入物特性可能如何影响其发病机制,因为ALCL仅发生在使用表面有纹理的植入物的女性中。
Materials (Basel). 2018-11-28
Ann Transl Med. 2023-10-25
Aesthet Surg J. 2017-9-1
Plast Reconstr Surg Glob Open. 2025-8-5
BMC Microbiol. 2025-7-2
Aesthet Surg J. 2024-11-15
Plast Reconstr Surg. 2018-10
Plast Reconstr Surg. 2018-4
J Mech Behav Biomed Mater. 2017-6-27
Plast Reconstr Surg. 2017-5
Plast Reconstr Surg. 2016-6
Arch Plast Surg. 2015-9