Wasserman K, Sietsema K E
Division of Respiratory and Critical Care Physiology and Medicine, Harbor-UCLA Medical Center, Torrance.
Cardiology. 1988;75(4):307-10. doi: 10.1159/000174390.
Exercise stresses the primary function of the cardiovascular system, which is the supply of O2 and removal of CO2 from the cells of the body. Even ordinary walking requires an increase in O2 consumption and CO2 production by the exercising muscles of 20 times the resting level. While pulmonary dysfunction may affect arterial blood gas tensions, the dynamics of O2 uptake and CO2 output by the lungs depend on the circulatory responses to exercise. Thus, measurement of the dynamics of O2 uptake in response to exercise has been shown to reflect cardiovascular function. Inability of the circulatory responses to meet an increased O2 requirement may be reflected in abnormalities in O2 uptake dynamics, and an early increase in CO2 output relative to O2 uptake consequent to bicarbonate buffering of lactic acid. Application of currently available technology for the continuous measurement and analysis of pulmonary gas exchange can afford the practicing or investigative cardiologist with a noninvasive and inexpensive means for assessing cardiovascular function.
运动强调心血管系统的主要功能，即向身体细胞供应氧气并清除二氧化碳。即使是普通的行走也需要运动肌肉的氧气消耗量和二氧化碳产生量增加到静息水平的20倍。虽然肺功能障碍可能会影响动脉血气张力，但肺部对氧气的摄取和二氧化碳的排出动态取决于循环系统对运动的反应。因此，测量运动时氧气摄取的动态变化已被证明可以反映心血管功能。循环反应无法满足增加的氧气需求可能会反映在氧气摄取动态的异常中，以及由于乳酸的碳酸氢盐缓冲作用，二氧化碳排出量相对于氧气摄取量过早增加。应用目前可用的技术对肺气体交换进行连续测量和分析，可以为执业或研究心脏病专家提供一种无创且廉价的评估心血管功能的方法。
