Limited information is available regarding the effective use of workplace head-worn displays (HWD), especially the choices of HWD types and user interface (UI) designs. We explored how different HWD types and UI designs affect perceived workload, usability, visual discomfort, and job performance during a simulated warehouse job involving order picking and part assembly. Sixteen gender-balanced participants completed the simulated job in all combinations of two HWD types (binocular vs. monocular) and four UIs, the latter of which manipulated information mode (text-vs. graphic-based) and information availability (always-on vs. on-demand); a baseline condition was also completed (paper pick list). Job performance, workload, and usability were more affected by UI designs than HWD type. For example, the graphic-based UI reduced job completion time and number of errors by ∼13% and ∼59%, respectively. Participants had no strong preference for either of the HWD types, suggesting that the physical HWD designs tested are suboptimal.