Omelyanenko N P, Mishina E S, Kovalev A V, Volkov A V
N. N. Priorov Central Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Moscow, Russia.
Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia.
Bull Exp Biol Med. 2018 Dec;166(2):274-278. doi: 10.1007/s10517-018-4331-3. Epub 2018 Nov 28.
Structural dynamics of the fibrous basis of the reparative regenerate during spontaneous skin wound healing comprises multiple stages, it successively transforms from one organization level to another more complex level, forms a multilevel 3D structure including molecular, supramolecular, fibrillar, fiber, and tissue elements. The formed reparative regenerate is integrated with the preserved skin, together they have common fibrous basis consisting of three parts that are different in organization of fibrous structures: atypical (central), tissue organospecific (peripheral), and transitional.
自发性皮肤伤口愈合过程中修复性再生纤维基质的结构动力学包括多个阶段，它依次从一个组织水平转变为另一个更复杂的水平，形成一个包括分子、超分子、纤维状、纤维和组织成分的多层次三维结构。形成的修复性再生组织与保留的皮肤整合在一起，它们共同拥有由纤维结构组织不同的三个部分组成的共同纤维基质：非典型（中央）、组织器官特异性（外周）和过渡性。
