Kim M S
Harvard Medical School, Boston, Massachusetts.
Clin Lab Med. 1988 Sep;8(3):527-40.
Proteinuria is one of the most common manifestations of renal disease. Changes in plasma protein concentration, glomerular permeability, tubular reabsorption, or renal hemodynamics can affect the rate of urinary excretion and the composition of urinary proteins. Determination of the significance of the proteinuria requires an evaluation of the amount and type of proteinuria in the context of the clinical setting. In addition, the clinician must be familiar with the laboratory evaluation of proteinuria and its limitations in order to correctly interpret these tests.
蛋白尿是肾脏疾病最常见的表现之一。血浆蛋白浓度、肾小球通透性、肾小管重吸收或肾血流动力学的变化会影响尿排泄率和尿蛋白的组成。确定蛋白尿的意义需要在临床背景下评估蛋白尿的量和类型。此外，临床医生必须熟悉蛋白尿的实验室评估及其局限性，以便正确解读这些检查。
