Nangia Ashwini K, Desiraju Gautam R
CSIR-National Chemical Laboratory, Homi Bhabha Road, Pune, 411 008, India.
School of Chemistry, University of Hyderabad, P.O. Central University, Hyderabad, 500 034, India.
Angew Chem Int Ed Engl. 2019 Mar 22;58(13):4100-4107. doi: 10.1002/anie.201811313. Epub 2019 Feb 27.
Crystal Engineering has traditionally dealt with molecular crystals. It is the understanding of intermolecular interactions in the context of crystal packing and in the utilization of such understanding in the design of new solids with desired physical and chemical properties. We outline here five areas which come under the umbrella of Crystal Engineering and where we feel that a proper planning of research efforts could lead to higher dividends for science together with greater returns for humankind. We touch on themes and domains where science funding and translation efforts could be directed in the current climate of a society that increasingly expects applications and utility products from science and technology. The five topics are: 1) pharmaceutical solids; 2) industrial solid state reactions; 3) mechanical properties with practical applications; 4) MOFs and COFs framework solids; 5) new materials for solar energy harvesting and advanced polymers.
传统上，晶体工程主要涉及分子晶体。它是在晶体堆积的背景下对分子间相互作用的理解，以及在设计具有所需物理和化学性质的新固体中对这种理解的运用。我们在此概述晶体工程涵盖的五个领域，我们认为在这些领域中，对研究工作进行适当规划能够为科学带来更高的回报，同时为人类带来更大的收益。我们探讨了一些主题和领域，在当今社会日益期望从科学技术中获得应用和实用产品的大环境下，科学资金和转化工作可以朝着这些方向进行。这五个主题是：1）药物固体；2）工业固态反应；3）具有实际应用的机械性能；4）金属有机框架（MOFs）和共价有机框架（COFs）骨架固体；5）用于太阳能收集的新材料和先进聚合物。
