Merrion Fertility Clinic-Reproductive Medicine Unit, Dublin 2, Ireland.
Department of Gynaecology, National Maternity Hospital, Dublin 2, Ireland.
J Psychosom Obstet Gynaecol. 2020 Mar;41(1):30-37. doi: 10.1080/0167482X.2018.1541980. Epub 2018 Nov 29.
: Significant medical benefits could be derived from universal AMH screening for women in their mid to late twenties. We aimed to investigate the psychological and emotional responses of women to being informed of their anti-Mullerian hormone (AMH) result with a view to informing the possible introduction of universal AMH screening.: This was a prospective qualitative study using semi-structured in-depth interviews of women attending a reproductive medicine clinic who had ovarian reserve testing performed via measurement of serum AMH levels, as part of their gynecological investigations. A semistructured interview schedule was developed after a review of the literature. A purposive sample of women was recruited, and data collection continued until thematic saturation was reached ( = 10). The number of women interviewed is low as this was a pilot qualitative study of a two-part study. The next part of the study involves the development of a quantitative questionnaire related to the key themes identified in this study to be based on a much larger group of women. Interviews were audiotaped, transcribed verbatim and imported into QSR NVivo pro 11 for analysis. Three key themes emerged from the data: the experience of AMH testing, the response to the AMH result, and suggested lessons for medical professionals. The theme of the experience of AMH testing describes and reflects two sub-themes: the reasons for ovarian reserve testing and the potential barriers that may prevent women from accessing testing. A further key focus of this study was the emotional and psychological responses to receiving an AMH result and this emerged as a major theme in the interviews. Women described the significant impact that their individual result had on a number of lifestyle and behavioral factors and how it impacted on their gender identity. Lessons for medical professionals including the appreciation of the patient's awareness of the test and how the test result was relayed to the patient were important factors in how they dealt with the result. There were mixed reactions and opinions from the group in relation to the introduction of AMH testing as a screening tool for all young women. Knowledge and communication of a low AMH result has a negative psychological impact. The findings from this study support the move to further explore the psychological and emotional impact of the test with the development of a quantitative questionnaire.
: 通过对血清抗苗勒管激素(AMH)水平的检测进行卵巢储备功能测试,为就诊于生殖医学门诊的女性提供 AMH 检测,这可能会为女性带来显著的医学获益。本研究旨在探讨女性对 AMH 检测结果的心理和情绪反应,以为 AMH 普遍筛查的引入提供信息。: 这是一项前瞻性定性研究,纳入了因妇科检查而进行卵巢储备功能测试的女性,对其进行基于 AMH 检测结果的生殖医学门诊就诊者进行半结构式深入访谈。在文献回顾后制定了半结构式访谈方案。采用目的性抽样方法招募女性,在达到主题饱和( = 10)时继续收集数据。由于这是一项关于两部分研究的初步定性研究,因此接受访谈的女性人数较少。下一步研究将开发一个与本研究中确定的关键主题相关的定量问卷,该问卷基于更大的女性群体。对访谈进行录音、逐字转录并导入 QSR NVivo pro 11 进行分析。研究结果共出现三个关键主题:AMH 检测体验、对 AMH 检测结果的反应以及对医学专业人员的建议。主题描述并反映了 AMH 检测体验的两个子主题:卵巢储备检测的原因和可能阻碍女性接受检测的潜在障碍。本研究的另一个重点是对接受 AMH 检测结果的情绪和心理反应,这在访谈中是一个主要主题。女性描述了其个人结果对许多生活方式和行为因素的重大影响,以及它如何影响其性别认同。对医学专业人员的建议包括对患者对检测的认识以及向患者传达检测结果的重视,这是他们处理检测结果的重要因素。该小组对 AMH 检测作为所有年轻女性的筛查工具的引入存在不同的看法。对 AMH 低值结果的认识和交流对心理产生负面影响。本研究结果支持进一步探讨该检测的心理和情绪影响,方法是开发一个定量问卷。