Thomsen H S, Løkkegaard H, Nielsen S L, Larsen S
Department of Nuclear Medicine, Herlev Hospital, Denmark.
Dan Med Bull. 1988 Aug;35(4):395-7.
Renal allograft dysfunction arising from rejection or cyclosporin A nephrotoxicity in patients on high-dose cyclosporin A administration can currently only be distinguished reliably by allograft biopsy excluding rejection. The renographic course up to 35 days after transplantation or to discharge was followed in 30 patients treated with low-dose azathioprine, prednisone, and cyclosporin A (triple therapy). Routine renographic monitoring combined with intravenous angiography in critical periods proved a valuable aid in the differentiation between post-operative complications such as acute rejection and surgical complications.
在接受大剂量环孢素 A 治疗的患者中，由排斥反应或环孢素 A 肾毒性引起的同种异体肾移植功能障碍目前只能通过排除排斥反应的同种异体肾活检来可靠区分。对 30 例接受低剂量硫唑嘌呤、泼尼松和环孢素 A（三联疗法）治疗的患者进行了移植后 35 天或出院前的肾图检查。在关键时期，常规肾图监测与静脉血管造影相结合被证明对区分急性排斥反应等术后并发症和手术并发症很有帮助。
