Neumann G
HNO. 1988 Sep;36(9):345-54.
Between 1952 and 1986 the mortality from malignant tumours of the head and neck in the German Federal Republic shows a varying picture: a decline of cancer of the lip, equivocal rates for cancer of the nose and ear, increases for cancer of the tongue and of the larynx, a marked increase for cancer of the floor of the mouth and of the hypopharynx, a lesser increase for cancer of the tonsillar area and other parts of the mouth, but almost no increase for cancer of the salivary glands. The trends are similar for males and females, but the male:female ratio increased during the observation period. The increase of mortality begins in the middle age group. Based on the data of the cancer registry of the Saarland it can be estimated that on average the incidence is twice as high as mortality. In general the trend is similar both in incidence and mortality (but not the degree of the trend). Multiple malignancies of the head and neck are observed more often than expected and patients should be followed up carefully. Combined clinical-epidemiological studies are needed.
1952年至1986年间,德意志联邦共和国头颈部恶性肿瘤的死亡率呈现出不同的情况:唇部癌症死亡率下降,鼻癌和耳癌死亡率变化不明确,舌癌和喉癌死亡率上升,口底癌和下咽癌死亡率显著上升,扁桃体区和口腔其他部位癌症死亡率上升幅度较小,而唾液腺癌死亡率几乎没有上升。男性和女性的趋势相似,但在观察期内男女比例有所增加。死亡率的上升始于中年组。根据萨尔州癌症登记处的数据估计,平均发病率是死亡率的两倍。总体而言,发病率和死亡率的趋势相似(但趋势程度不同)。头颈部多原发恶性肿瘤的观察频率高于预期,应对患者进行仔细随访。需要开展临床与流行病学相结合的研究。