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Where Is the Opioid Use Epidemic in Mexico? A Cautionary Tale for Policymakers South of the US-Mexico Border.墨西哥的阿片类药物使用泛滥问题出在哪里?对美国-墨西哥边境以南的政策制定者的一个警示故事。
Am J Public Health. 2019 Jan;109(1):73-82. doi: 10.2105/AJPH.2018.304767. Epub 2018 Nov 29.
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The US Opioid Crisis: Current Federal and State Legal Issues.美国阿片类药物危机:当前联邦和州的法律问题。
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Opioid Analgesics in Georgia Medicaid: Trends in Potential Inappropriate Prescribing Practices by Demographic Characteristics, 2009-2014.佐治亚州医疗补助计划中的阿片类镇痛药:2009 - 2014年按人口特征划分的潜在不适当处方行为趋势
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Prescription opioid related misuse, harms, diversion and interventions in Canada: a review.加拿大与处方阿片类药物相关的滥用、危害、转移和干预措施:综述。
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Systematic Evaluation of State Policy Interventions Targeting the US Opioid Epidemic, 2007-2018.系统评价针对美国阿片类药物流行的国家政策干预措施,2007-2018 年。
JAMA Netw Open. 2021 Feb 1;4(2):e2036687. doi: 10.1001/jamanetworkopen.2020.36687.
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The prescription opioid and heroin crisis: a public health approach to an epidemic of addiction.处方阿片类药物和海洛因危机:一种公共卫生方法应对成瘾的流行。
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Opioid epidemic in the United States.美国的阿片类药物泛滥问题。
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Reframing the Prevention Strategies of the Opioid Crisis: Focusing on Prescription Opioids, Fentanyl, and Heroin Epidemic.重新构建阿片类药物危机的预防策略:聚焦处方阿片类药物、芬太尼和海洛因流行。
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The opioid crisis: Origins, trends, policies, and the roles of pharmacists.阿片类药物危机:起源、趋势、政策以及药剂师的作用。
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Spatial Heterogeneity in Fatal Overdose Rate Trends in Mexican Cities: 2005-2021.墨西哥城市致命过量率趋势的空间异质性:2005-2021 年。
Am J Public Health. 2024 Jul;114(7):705-713. doi: 10.2105/AJPH.2024.307650. Epub 2024 May 9.
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Implementing a decentralized opioid overdose prevention strategy in Mexico, a pending public policy issue.在墨西哥实施分散式阿片类药物过量预防策略,这是一个悬而未决的公共政策问题。
Lancet Reg Health Am. 2023 Jun 17;23:100535. doi: 10.1016/j.lana.2023.100535. eCollection 2023 Jul.
3
Fentanyl, heroin, and methamphetamine-based counterfeit pills sold at tourist-oriented pharmacies in Mexico: An ethnographic and drug checking study.在墨西哥面向游客的药店出售的芬太尼、海洛因和冰毒为基础的假冒药丸:一项民族志和药物检测研究。
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Fentanyl, Heroin, and Methamphetamine-Based Counterfeit Pills Sold at Tourist-Oriented Pharmacies in Mexico: An Ethnographic and Drug Checking Study.墨西哥面向游客的药店出售的基于芬太尼、海洛因和甲基苯丙胺的假药:一项人种志与药物检测研究。
medRxiv. 2023 May 31:2023.01.27.23285123. doi: 10.1101/2023.01.27.23285123.
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The introduction of fentanyl on the US-Mexico border: An ethnographic account triangulated with drug checking data from Tijuana.芬太尼在美国-墨西哥边境的引入:来自蒂华纳毒品检测数据的三角民族志描述。
Int J Drug Policy. 2022 Jun;104:103678. doi: 10.1016/j.drugpo.2022.103678. Epub 2022 Apr 11.
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Investigating a bidirectional relationship between overdose and provision of injection initiation assistance among persons who inject drugs in Vancouver, Canada and Tijuana, Mexico.调查加拿大温哥华和墨西哥蒂华纳注射吸毒者中过量用药和提供注射起始协助之间的双向关系。
Int J Drug Policy. 2021 Sep;95:103398. doi: 10.1016/j.drugpo.2021.103398. Epub 2021 Aug 12.
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Involvement of people who inject drugs in injection initiation events: a cross-sectional analysis identifying similarities and differences across three North American settings.注射吸毒者参与注射起始事件:一项横断面分析,确定了三个北美环境中的相似点和不同点。
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Geographical and socioeconomic disparities in opioid access in Mexico, 2015-19: a retrospective analysis of surveillance data.墨西哥阿片类药物获取的地理和社会经济差异,2015-19 年:监测数据的回顾性分析。
Lancet Public Health. 2021 Feb;6(2):e88-e96. doi: 10.1016/S2468-2667(20)30260-7.
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Examining the gender composition of drug injecting initiation events: A mixed methods investigation of three North American contexts.考察药物注射起始事件的性别构成:对三个北美背景的混合方法调查。
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本文引用的文献

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Cost of provision of opioid substitution therapy provision in Tijuana, Mexico.墨西哥提华纳提供阿片类药物替代疗法的成本。
Harm Reduct J. 2018 May 23;15(1):28. doi: 10.1186/s12954-018-0234-x.
2
Injection Drug Use Trajectories among Migrant Populations: A Narrative Review.流动人群中的注射吸毒轨迹:一项叙述性综述
Subst Use Misuse. 2018 Jul 29;53(9):1558-1570. doi: 10.1080/10826084.2017.1416404. Epub 2018 Jan 24.
3
Alleviating the access abyss in palliative care and pain relief-an imperative of universal health coverage: the Lancet Commission report.缓解姑息治疗和疼痛缓解方面的获取差距——全民健康覆盖的当务之急:《柳叶刀》委员会报告
Lancet. 2018 Apr 7;391(10128):1391-1454. doi: 10.1016/S0140-6736(17)32513-8. Epub 2017 Oct 12.
4
Prescription drug monitoring program design and function: A qualitative analysis.处方药监测项目的设计与功能:一项定性分析
Drug Alcohol Depend. 2017 Nov 1;180:395-400. doi: 10.1016/j.drugalcdep.2017.08.040. Epub 2017 Sep 28.
5
History of medication-assisted treatment and its association with initiating others into injection drug use in San Diego, CA.加利福尼亚州圣地亚哥的药物辅助治疗历史及其与注射吸毒者的关系。
Subst Abuse Treat Prev Policy. 2017 Oct 3;12(1):42. doi: 10.1186/s13011-017-0126-1.
6
Time-Series Analysis of the Impact of Prescription Drug Monitoring Programs on Heroin Treatment Admissions.处方药监测计划对海洛因治疗入院影响的时间序列分析
Subst Use Misuse. 2018 Mar 21;53(4):694-701. doi: 10.1080/10826084.2017.1363232. Epub 2017 Sep 27.
7
Impact of New York prescription drug monitoring program, I-STOP, on statewide overdose morbidity.纽约处方药监测计划(I-STOP)对全州过量用药发病率的影响。
Drug Alcohol Depend. 2017 Sep 1;178:348-354. doi: 10.1016/j.drugalcdep.2017.05.023. Epub 2017 Jun 23.
8
Evaluating the impact of prescription drug monitoring program implementation: a scoping review.评估处方药监测计划实施的影响:一项范围综述
BMC Health Serv Res. 2017 Jun 20;17(1):420. doi: 10.1186/s12913-017-2354-5.
9
Health-damaging policing practices among persons who inject drugs in Mexico: Are deported migrants at greater risk?墨西哥注射吸毒者中有害健康的治安执法行为:被驱逐的移民风险更高吗?
Int J Drug Policy. 2017 Aug;46:41-46. doi: 10.1016/j.drugpo.2017.05.028. Epub 2017 Jun 7.
10
Increased use of heroin as an initiating opioid of abuse.海洛因作为滥用起始阿片类药物的使用增加。
Addict Behav. 2017 Nov;74:63-66. doi: 10.1016/j.addbeh.2017.05.030. Epub 2017 May 23.

墨西哥的阿片类药物使用泛滥问题出在哪里?对美国-墨西哥边境以南的政策制定者的一个警示故事。

Where Is the Opioid Use Epidemic in Mexico? A Cautionary Tale for Policymakers South of the US-Mexico Border.

机构信息

David Goodman-Meza and Raphael J. Landovitz are with Division of Infectious Diseases, David Geffen School of Medicine at University of California Los Angeles (UCLA). Raphael J. Landovitz is also with Center for Clinical AIDS Research and Education, Los Angeles. Maria Elena Medina-Mora is with Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City, Mexico. Carlos Magis-Rodríguez is with National Center for the Prevention and Control of HIV and AIDS, Mexico City. Steve Shoptaw is with Department of Family Medicine, David Geffen School of Medicine at UCLA. Dan Werb is with Department of Medicine, University of California San Diego, La Jolla.

出版信息

Am J Public Health. 2019 Jan;109(1):73-82. doi: 10.2105/AJPH.2018.304767. Epub 2018 Nov 29.

DOI:10.2105/AJPH.2018.304767
PMID:30495992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6301408/
Abstract

In North America, opioid use and its harms have increased in the United States and Canada over the past 2 decades. However, Mexico has yet to document patterns suggesting a higher level of opioid use or attendant harms.Historically, Mexico has been a country with low-level use of opioids, although heroin use has been documented. Low-level opioid use is likely attributable to structural, cultural, and individual factors. However, a range of dynamic factors may be converging to increase the use of opioids: legislative changes to opioid prescribing, national health insurance coverage of opioids, pressure from the pharmaceutical industry, changing demographics and disease burden, forced migration and its trauma, and an increase in the production and trafficking of heroin. In addition, harm-reduction services are scarce.Mexico may transition from a country of low opioid use to high opioid use but has the opportunity to respond effectively through a combination of targeted public health surveillance of high-risk groups, preparation of appropriate infrastructure to support evidence-based treatment, and interventions and policies to avoid a widespread opioid use epidemic.

摘要

在北美,过去 20 年来,美国和加拿大的阿片类药物使用及其危害不断增加。然而,墨西哥尚未记录表明阿片类药物使用水平更高或伴随危害更大的模式。从历史上看,墨西哥一直是一个阿片类药物使用水平较低的国家,尽管有记录表明存在海洛因使用情况。低水平的阿片类药物使用可能归因于结构性、文化性和个体性因素。然而,一系列动态因素可能正在汇聚,导致阿片类药物使用增加:阿片类药物处方的立法改革、国家医疗保险覆盖阿片类药物、制药行业的压力、人口结构和疾病负担的变化、被迫迁移及其创伤,以及海洛因产量和贩运的增加。此外,减少伤害服务稀缺。墨西哥可能会从一个阿片类药物使用水平较低的国家过渡到一个阿片类药物使用水平较高的国家,但有机会通过对高风险群体进行有针对性的公共卫生监测、准备适当的基础设施以支持基于证据的治疗,以及采取干预措施和政策来避免广泛的阿片类药物使用流行,从而做出有效应对。