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[掌腱膜纤维瘤病(杜普伊特伦氏病)。比较临床、病理及解剖学肿块检查(作者译)]

[Palmar fibromatosis (morbus Dupuytren). Comparative clinical, pathological and anatomical mass examinations (author's transl)].

作者信息

Meister P, Wilhelm K, Röckl C

出版信息

MMW Munch Med Wochenschr. 1978 Jan 27;120(4):93-8.

PMID:304964
Abstract

Classification (119 patients) of age, sex and side distributions and the frequency of additional fibromatoses or other diseases in palmar fibromatosis (Morbus Dupuytren) showed extensive agreement with other investigations. Contractures were also found in mutiple foci with high cell density and without intensive collagen fiber formation corresponding to the proliferative or involution phase. Cells with contractile elements ("myofibroblasts") could also be demonstrated with both electron and immunofluorescence microscopes. These elements may be of importance for the formation of the contracture in palmar fibromatosis and may disappear again as the collagen becomes more mature.

摘要

掌腱膜纤维瘤病(杜普伊特伦氏病)患者年龄、性别及患病部位分布的分类(119例患者)以及合并其他纤维瘤病或其他疾病的频率,与其他研究结果高度一致。在多个病灶中还发现了挛缩,这些病灶细胞密度高,且未出现与增殖期或消退期相对应的密集胶原纤维形成。通过电子显微镜和免疫荧光显微镜均可证实具有收缩成分的细胞(“肌成纤维细胞”)。这些成分可能在掌腱膜纤维瘤病挛缩的形成中起重要作用,并且可能随着胶原变得更加成熟而再次消失。

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