Friedman S J, Butler D F, Pittelkow M R
Department of Internal Medicine, William Beaumont Army Medical Center, El Paso, TX.
J Am Acad Dermatol. 1988 Sep;19(3):537-41. doi: 10.1016/s0190-9622(88)70209-1.
We report on the cases of two patients in whom linear perilesional hypopigmentation and atrophy developed after intralesional injection of corticosteroids for treatment of keloids. Evaluation of our patients and the previously reported cases showed that perilesional linear atrophy or hypopigmentation (or both) is a distinct complication after intralesional or intraarticular administration of corticosteroids and is probably due to lymphogenous spread of the steroid suspension.
我们报告了两例患者的病例，这两名患者在病灶内注射皮质类固醇治疗瘢痕疙瘩后出现了病灶周围线性色素减退和萎缩。对我们的患者以及先前报道病例的评估表明，病灶周围线性萎缩或色素减退（或两者皆有）是病灶内或关节内注射皮质类固醇后的一种独特并发症，可能是由于类固醇混悬液的淋巴源性扩散所致。
