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线性皮肤色素减退伴萎缩与皮损内类固醇注射相关:一种罕见的不良反应。

Linear cutaneous hypopigmentation and atrophy associated with intralesional steroid injection: A rarely described adverse reaction.

机构信息

Dermatology Department, Sapienza University of Rome, Rome, Italy.

Department of Dermatology, Sapienza University of Rome, Rome, Italy.

出版信息

Dermatol Ther. 2019 Jul;32(4):e12941. doi: 10.1111/dth.12941. Epub 2019 May 3.

DOI:10.1111/dth.12941
PMID:31012196
Abstract

Intralesional steroid injection is a common and highly effective treatment procedure, which can be successfully used for several dermatologic, rheumatologic, and orthopedic disorders. However, it may be associated with various local side effects, such as pain, granulomatous reaction, allergic reactions, hypo or hyperpigmentation and, uncommonly, skin atrophy. A peculiar and rare side effect of steroid injection is linear hypopigmentation and atrophy, which is probably an expression of lymphatic spread of corticosteroid crystals. Here, we report a case of linear hypopigmentation and atrophy in a 26-year-old male patient.

摘要

病灶内类固醇注射是一种常见且非常有效的治疗方法,可成功用于多种皮肤科、风湿科和骨科疾病。然而,它可能与各种局部副作用相关,如疼痛、肉芽肿反应、过敏反应、色素减退或沉着,以及不常见的皮肤萎缩。类固醇注射的一种特殊且罕见的副作用是线性色素减退和萎缩,这可能是皮质类固醇晶体淋巴管扩散的表现。在此,我们报告了一例 26 岁男性患者的线性色素减退和萎缩病例。

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Linear cutaneous hypopigmentation and atrophy associated with intralesional steroid injection: A rarely described adverse reaction.线性皮肤色素减退伴萎缩与皮损内类固醇注射相关:一种罕见的不良反应。
Dermatol Ther. 2019 Jul;32(4):e12941. doi: 10.1111/dth.12941. Epub 2019 May 3.
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