皮肤转移。
Cutaneous Metastasis.
机构信息
James Graham Brown Cancer Center, University of Louisville School of Medicine, 529 S. Jackson Street, Louisville, KY 40202, USA; Department of Dermatology, Center for Cancer Immunology and Cutaneous Biology Research Center, MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
James Graham Brown Cancer Center, University of Louisville School of Medicine, 529 S. Jackson Street, Louisville, KY 40202, USA.
出版信息
Hematol Oncol Clin North Am. 2019 Feb;33(1):173-197. doi: 10.1016/j.hoc.2018.08.008.
Although rare, cutaneous metastases portend a poor prognosis and are often an indicator of widespread disease. Breast cancer and melanoma are the most common types of cancer that are associated with spread to and within the skin; however, other malignancies, such as lung, colon, head and neck, and hematologic, have been described with a degree of relative frequency. A variety of clinical appearances and syndromes of cutaneous metastases are presented and described in this article. Possible treatment options, including skin-directed therapies and immunotherapies, are also discussed.
虽然罕见，但皮肤转移预示着预后不良，通常也是广泛疾病的标志。乳腺癌和黑色素瘤是最常见的与皮肤转移和皮肤内转移相关的癌症类型；然而，其他恶性肿瘤，如肺癌、结肠癌、头颈部和血液系统恶性肿瘤，也有一定程度的相对频率被描述。本文介绍并描述了各种皮肤转移的临床表现和综合征。还讨论了可能的治疗选择，包括皮肤靶向治疗和免疫疗法。
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