• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

乳腺癌皮肤转移:病例报告。

Cutaneous Metastasis in Breast Cancer: A Case Report.

机构信息

Department of Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

Gastrointestinal Oncology Unit, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

出版信息

Am J Case Rep. 2024 Jul 12;25:e943999. doi: 10.12659/AJCR.943999.

DOI:10.12659/AJCR.943999
PMID:38992932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11315621/
Abstract

BACKGROUND Breast cancer (BC) is the most common malignant disease in females and one of the leading causes of death worldwide. Its treatment plan includes a long-term follow-up and close surveillance, as recurrence is a well-acknowledged concern. BC can recur either locally or as a metastasis, and skin metastasis is a common complication in advanced breast cancer patients. It can present as a skin nodule, plaque, or erythematous lesion, and can be difficult to distinguish from benign skin conditions. The risk of skin metastasis is higher in patients with inflammatory BC. Treatment of such a complex condition is even more challenging, with poor prognosis. Here, we report a case of a 42-year-old woman with stage 4 luminal A BC who had soft tissue recurrence. CASE REPORT A 42-year-old woman with a history of left-sided BC diagnosed and treated 10 years ago presented with multiple soft tissue masses mimicking abscesses at the right lower middle of the back, bilateral thighs, and back of the neck, in the last 6 months, the largest measuring 8×10 cm. The masses were found to be metastatic BC that had spread to the skin and lungs. Because it was invasive ductal carcinoma with positive ER and PR receptors, she was started on hormonal treatment and chemotherapy. CONCLUSIONS This case report highlights the importance of follow-up in patients with a history of BC, as the cancer can recur and spread many years after treatment.

摘要

背景

乳腺癌(BC)是女性最常见的恶性疾病之一,也是全球死亡的主要原因之一。其治疗方案包括长期随访和密切监测,因为复发是一个公认的关注点。BC 可以局部复发或转移,皮肤转移是晚期乳腺癌患者的常见并发症。它可以表现为皮肤结节、斑块或红斑性病变,并且很难与良性皮肤状况区分。炎症性 BC 患者发生皮肤转移的风险更高。治疗这种复杂的情况更加具有挑战性,预后较差。在这里,我们报告了一例 42 岁女性,患有 4 期 luminal A 型 BC,软组织复发。

病例报告

一名 42 岁女性,10 年前曾诊断并治疗左侧 BC,最近 6 个月出现右侧中下背部、双侧大腿和颈部后侧多个软组织肿块,类似于脓肿,最大的肿块为 8×10cm。这些肿块被发现是转移性 BC,已经扩散到皮肤和肺部。由于它是浸润性导管癌,ER 和 PR 受体阳性,她开始接受激素治疗和化疗。

结论

本病例报告强调了对有 BC 病史的患者进行随访的重要性,因为癌症在治疗后多年可能会复发和转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/32908e91bd5f/amjcaserep-25-e943999-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/3676c00e1914/amjcaserep-25-e943999-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/f6bbed747bc2/amjcaserep-25-e943999-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/94e45fc7f2b9/amjcaserep-25-e943999-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/32908e91bd5f/amjcaserep-25-e943999-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/3676c00e1914/amjcaserep-25-e943999-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/f6bbed747bc2/amjcaserep-25-e943999-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/94e45fc7f2b9/amjcaserep-25-e943999-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae08/11315621/32908e91bd5f/amjcaserep-25-e943999-g004.jpg

相似文献

1
Cutaneous Metastasis in Breast Cancer: A Case Report.乳腺癌皮肤转移:病例报告。
Am J Case Rep. 2024 Jul 12;25:e943999. doi: 10.12659/AJCR.943999.
2
Folliculotropic Cutaneous Metastases and Lymphangitis Carcinomatosa: When Cutaneous Metastases of Breast Carcinoma Are Mistaken for Cutaneous Infections.毛囊性皮肤转移瘤和癌性淋巴管炎:乳腺癌皮肤转移被误诊为皮肤感染时的情况。
Acta Dermatovenerol Croat. 2016 Jun;24(2):154-7.
3
Erythematous nodules of the hand: a rare site of metastatic breast carcinoma.手部红斑性结节:转移性乳腺癌的罕见部位。
Indian J Dermatol Venereol Leprol. 2011 Nov-Dec;77(6):695-8. doi: 10.4103/0378-6323.86484.
4
Cutaneous metastasis of breast carcinoma mimicking malignant melanoma in scalp.头皮部酷似恶性黑色素瘤的乳腺癌皮肤转移
Dermatol Online J. 2008 Nov 15;14(11):12.
5
Surviving metastatic breast cancer for 18 years: a case report and review of the literature.转移性乳腺癌存活 18 年 1 例报告及文献复习
Breast J. 2011 Sep-Oct;17(5):521-4. doi: 10.1111/j.1524-4741.2011.01123.x. Epub 2011 Jul 5.
6
Breast carcinoma en Cuirasse--case report.铠甲状乳腺癌——病例报告
An Bras Dermatol. 2013 Jul-Aug;88(4):608-10. doi: 10.1590/abd1806-4841.20131926.
7
Erysipelatoid Carcinoma.类丹毒样癌
Rev Assoc Med Bras (1992). 2018 Jun;64(6):492-497. doi: 10.1590/1806-9282.64.06.492.
8
Gastric Metastasis Mimicking Early Gastric Cancer from Invasive Ductal Carcinoma of the Breast: Case Report and Literature Review.胃转移癌酷似乳腺癌浸润性导管癌的早期胃癌:病例报告及文献复习。
Medicina (Kaunas). 2024 Jun 13;60(6):980. doi: 10.3390/medicina60060980.
9
Breast and pleuropulmonary metastasis of multirecurrent scalp dermatofibrosarcoma protuberans: a case report.多复发性头皮隆突性皮肤纤维肉瘤的乳腺及胸膜肺转移:1例报告
J Med Case Rep. 2017 Apr 8;11(1):96. doi: 10.1186/s13256-017-1257-8.
10
Cutaneous metastatic pigmented breast carcinoma.皮肤转移性色素沉着性乳腺癌
Dermatol Online J. 2016 Mar 16;22(3):13030/qt0sv018ck.

本文引用的文献

1
Cutaneous Metastasis in Breast Cancer: A Case Series.乳腺癌皮肤转移:病例系列
Cureus. 2023 Jun 8;15(6):e40109. doi: 10.7759/cureus.40109. eCollection 2023 Jun.
2
NCCN Guidelines® Insights: Breast Cancer, Version 4.2023.NCCN 指南®洞察:乳腺癌,第 4.2023 版。
J Natl Compr Canc Netw. 2023 Jun;21(6):594-608. doi: 10.6004/jnccn.2023.0031.
3
Breast Cancer Diagnosis and Survival among Patients Diagnosed by a Structured Community Based Screening Program Compared to Opportunistic Diagnosis: A Case Control Study.
基于社区的结构化筛查项目与机会性诊断对乳腺癌诊断和生存的影响:病例对照研究。
Asian Pac J Cancer Prev. 2023 Mar 1;24(3):923-927. doi: 10.31557/APJCP.2023.24.3.923.
4
The Clinicopathological features and survival outcomes of patients with different metastatic sites in stage IV breast cancer.IV 期乳腺癌不同转移部位患者的临床病理特征和生存结局。
BMC Cancer. 2019 Nov 12;19(1):1091. doi: 10.1186/s12885-019-6311-z.
5
A Multigene Assay Determines Risk of Recurrence in Patients with Triple-Negative Breast Cancer.多基因检测可确定三阴性乳腺癌患者的复发风险。
Cancer Res. 2019 Jul 1;79(13):3466-3478. doi: 10.1158/0008-5472.CAN-18-3014. Epub 2019 May 2.
6
Clinical features and prognosis of breast cancer with gastric metastasis.伴有胃转移的乳腺癌的临床特征及预后
Oncol Lett. 2019 Feb;17(2):1833-1841. doi: 10.3892/ol.2018.9754. Epub 2018 Nov 23.
7
Cutaneous Metastasis.皮肤转移。
Hematol Oncol Clin North Am. 2019 Feb;33(1):173-197. doi: 10.1016/j.hoc.2018.08.008.
8
Breast cancer metastasis to gynaecological organs: a clinico-pathological and molecular profiling study.乳腺癌转移至妇科器官:临床病理和分子特征研究。
J Pathol Clin Res. 2019 Jan;5(1):25-39. doi: 10.1002/cjp2.118. Epub 2018 Oct 22.
9
Outcomes of patients with inflammatory breast cancer by hormone receptor- and HER2-defined molecular subtypes: A population-based study from the SEER program.激素受体和HER2定义的分子亚型的炎性乳腺癌患者的预后:一项来自监测、流行病学和最终结果(SEER)计划的基于人群的研究。
Oncotarget. 2017 Jul 25;8(30):49370-49379. doi: 10.18632/oncotarget.17217.
10
Brain Metastases in Newly Diagnosed Breast Cancer: A Population-Based Study.新发乳腺癌脑转移:一项基于人群的研究。
JAMA Oncol. 2017 Aug 1;3(8):1069-1077. doi: 10.1001/jamaoncol.2017.0001.