Yazidi Dina, De Saint-Aubain Nicolas, Michiels Sebastien
Department of General Surgery, Centre Hospitalier Interrégional Edith Cavell (CHIREC), Brussels, BEL.
Department of Pathology, Jules Bordet Institut, Brussels, BEL.
Cureus. 2025 Jun 17;17(6):e86187. doi: 10.7759/cureus.86187. eCollection 2025 Jun.
Pilomatrixoma is a rare subcutaneous tumor originating from the cellular matrix of hair follicles. While it predominantly arises during the first two decades of life, its occurrence in elderly patients is exceedingly rare. We present the case of an 83-year-old woman with a recently growing, indurated nodule located on the right upper eyelid. Her medical history included left breast cancer treated with tumorectomy, radiotherapy, and chemotherapy, with remission since 2012. Given her advanced age and oncological history, differential diagnoses included malignant tumors, metastasis, or recurrence of breast cancer involving the head and neck region. Histopathological analysis confirmed the diagnosis of pilomatrixoma, which was completely excised with clear margins. The postoperative course was uneventful, and no recurrence was observed at one-month follow-up. This case highlights the importance of including pilomatrixoma in the differential diagnosis of head and neck lesions in elderly patients.
毛母质瘤是一种罕见的起源于毛囊细胞基质的皮下肿瘤。虽然它主要发生在生命的前二十年,但在老年患者中极为罕见。我们报告了一例83岁女性病例,其右上眼睑有一个近期生长的硬结性结节。她的病史包括接受肿瘤切除术、放疗和化疗的左乳腺癌,自2012年以来病情缓解。鉴于她的高龄和肿瘤病史,鉴别诊断包括恶性肿瘤、转移瘤或累及头颈部区域的乳腺癌复发。组织病理学分析确诊为毛母质瘤,并将其完整切除,切缘清晰。术后过程顺利,术后1个月随访未观察到复发。该病例强调了在老年患者头颈部病变的鉴别诊断中纳入毛母质瘤的重要性。