O'Reilly Daria J, Blackhouse Gord, Burns Sheri, Bowen James M, Burke Natasha, Mehltretter Jeff, Waite Nancy M, Houle Sherilyn Kd
Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada,
Programs for Assessment of Technology in Health (PATH), The Research Institute of St. Joe's Hamilton, Hamilton, ON, Canada,
Clinicoecon Outcomes Res. 2018 Oct 24;10:655-663. doi: 10.2147/CEOR.S167500. eCollection 2018.
The aim of this study was to evaluate the impact of pharmacist administration of influenza vaccine in Ontario on: 1) vaccination-associated costs related to the number of people vaccinated; 2) annual influenza-related outcomes and costs; and 3) change in productivity costs.
Using available data for Ontario, the total number of vaccinations given by providers in the 2011/12 influenza season (pre) was compared to the 2013/14 influenza season (post). Vaccine costs and provider fees for administration were assigned for both periods. An economic model was created to estimate the impact of the change in influenza vaccination volume on influenza-related outcomes and on the health care costs associated with treating influenza-related outcomes. Productivity costs due to both time off work due to getting vaccinated and influenza illness were considered. One-way sensitivity analysis was used to assess parameter uncertainty.
The number of vaccinations received by Ontarians increased by 448,000 (3% of the population), with pharmacists vaccinating approximately 765,000 people/year. The increased cost to the Ontario Ministry of Health and Long-term Care was $6.3 million, while the money saved due to reduced influenza-related outcome costs was $763,158. Productivity losses were reduced by $4.5 million and $3.4 million for the time invested to get vaccinated and time off work due to influenza illness, respectively.
After two influenza seasons, following the introduction of pharmacist-administered influenza vaccinations, there was a net immunization increase of almost 450,000, which potentially saved $2.3 million in direct health care costs and lost productivity in the province.
本研究旨在评估安大略省药剂师接种流感疫苗的影响,具体包括:1)与接种人数相关的疫苗接种成本;2)年度流感相关结果及成本;3)生产力成本的变化。
利用安大略省的现有数据,将2011/12流感季节(之前)提供者接种的疫苗总数与2013/14流感季节(之后)进行比较。两个时期都分配了疫苗成本和接种服务费。建立了一个经济模型,以估计流感疫苗接种量变化对流感相关结果以及与治疗流感相关结果相关的医疗成本的影响。考虑了因接种疫苗和患流感而请假导致的生产力成本。采用单向敏感性分析来评估参数不确定性。
安大略省居民接种疫苗的数量增加了44.8万(占人口的3%),药剂师每年接种约76.5万人。安大略省卫生和长期护理部增加的成本为630万美元,而因流感相关结果成本降低而节省的资金为763,158美元。因接种疫苗投入的时间和因患流感而请假导致的生产力损失分别减少了450万美元和340万美元。
在两个流感季节之后,引入药剂师接种流感疫苗后,净免疫人数增加了近45万,这可能为该省节省了230万美元的直接医疗成本和生产力损失。