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揭示分泌的秘密。

Revealing the secrets of secretion.

机构信息

Department of Pharmacology, University of Oxford, Oxford, United Kingdom.

出版信息

Elife. 2018 Nov 30;7:e43512. doi: 10.7554/eLife.43512.

DOI:10.7554/eLife.43512
PMID:30499445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6269119/
Abstract

An intracellular ion channel may have a central role in the release of cytokines by macrophages.

摘要

细胞内离子通道可能在巨噬细胞释放细胞因子中起核心作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e74/6269119/7d53098e84bd/elife-43512-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e74/6269119/7d53098e84bd/elife-43512-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e74/6269119/7d53098e84bd/elife-43512-fig1.jpg

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本文引用的文献

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2
Lysosomal Ion Channels as Decoders of Cellular Signals.溶酶体离子通道作为细胞信号的解码器。
Trends Biochem Sci. 2019 Feb;44(2):110-124. doi: 10.1016/j.tibs.2018.10.006. Epub 2018 Nov 10.
3
Small Molecules for Early Endosome-Specific Patch Clamping.小分子用于早期内体特异性膜片钳。
Cell Chem Biol. 2017 Jul 20;24(7):907-916.e4. doi: 10.1016/j.chembiol.2017.05.025.
4
Novel Role of TRPML2 in the Regulation of the Innate Immune Response.瞬时受体电位黏蛋白2(TRPML2)在先天性免疫反应调节中的新作用
J Immunol. 2015 Nov 15;195(10):4922-32. doi: 10.4049/jimmunol.1500163. Epub 2015 Oct 2.
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The mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function.黏脂素-2(TRPML2)离子通道:一种对正常细胞功能至关重要的组织特异性蛋白。
Pflugers Arch. 2016 Feb;468(2):177-92. doi: 10.1007/s00424-015-1732-2. Epub 2015 Sep 4.
6
CCL2-CCR2 Signaling in Disease Pathogenesis.疾病发病机制中的CCL2-CCR2信号传导
Endocr Metab Immune Disord Drug Targets. 2015;15(2):105-18. doi: 10.2174/1871530315666150316120920.
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The role of TRPMLs in endolysosomal trafficking and function.瞬时受体电位黏蛋白在内涵体溶酶体运输及功能中的作用。
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