Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Division of Vascular and Endovascular Surgery, School of Medicine, Boston University, Boston, MA.
Ann Surg. 2020 Jan;271(1):184-190. doi: 10.1097/SLA.0000000000002873.
We studied whether the volume-outcome relationship would persist in more complex aortic operations.
Despite the added complexity of the involvement of the renal arteries in open juxtarenal abdominal aortic aneurysm (AAA) repair, the volume effect in these difficult operations has yet to be defined.
We identified all patients in the Vascular Quality Initiative (VQI) who underwent open AAA repair from 2003 to 2016. We calculated each hospital's average annual volume for total open AAA repairs, and total open juxtarenal AAA repairs. We compared adjusted perioperative and long-term survival across quintiles of hospital volume, and constructed models including both volume metrics to evaluate the cross-volume effects.
Of 8880 total open AAA repairs, there were 3470 open juxtarenal cases. Centers with low (<4), medium (4-14), and high (>14) volumes of open juxtarenal repair demonstrated adjusted perioperative mortality of 9.0%, 4.9%, and 3.9%, respectively (P < 0.01). When both volume metrics were considered, open juxtarenal volume, but not total open AAA volume was associated with perioperative mortality (lowest quintile of juxtarenal volume: OR 2.36 [1.29-4.30], P < 0.01). Hospital volume was not associated with adjusted long-term mortality. High volume centers were more likely to use renal protective strategies such as mannitol and cold renal perfusion (both P < 0.01). Low volume centers performed a similar proportion of cases each year, but 22 centers (13%) did stop performing repairs during the study period.
Hospitals with low annualized volumes of open juxtarenal repair have higher perioperative mortality, irrespective of their total open aortic volume. Complex open AAA repairs should be performed at experienced centers, and future efforts should focus on centralization of complex aortic care.
我们研究了在更复杂的主动脉手术中,手术量与结果的关系是否仍然存在。
尽管开放型肾周腹主动脉瘤(AAA)修复术涉及到肾动脉,增加了手术的复杂性,但这些复杂手术的量效关系尚未确定。
我们在血管质量倡议(VQI)中确定了 2003 年至 2016 年间所有接受开放型 AAA 修复的患者。我们计算了每个医院进行全开放型 AAA 修复术和全开放型肾周 AAA 修复术的平均年手术量。我们比较了医院手术量五分位数组的调整后围手术期和长期生存率,并构建了包含两个手术量指标的模型,以评估交叉手术量的影响。
在 8880 例全开放型 AAA 修复中,有 3470 例开放型肾周 AAA 病例。低(<4)、中(4-14)和高(>14)手术量的中心,开放型肾周修复的调整后围手术期死亡率分别为 9.0%、4.9%和 3.9%(P < 0.01)。当同时考虑两个手术量指标时,开放型肾周手术量,而不是全开放型 AAA 手术量,与围手术期死亡率相关(肾周手术量最低五分位数:比值比 2.36[1.29-4.30],P < 0.01)。医院手术量与调整后的长期死亡率无关。高手术量中心更有可能采用甘露醇和低温肾灌注等肾脏保护策略(均 P < 0.01)。低手术量中心每年进行的手术量比例相似,但在研究期间,有 22 个中心(13%)停止进行修复手术。
每年开放型肾周 AAA 修复手术量较低的医院,其围手术期死亡率较高,而与总开放型主动脉手术量无关。复杂的开放型 AAA 修复应在有经验的中心进行,未来的努力应集中在复杂主动脉疾病的治疗中心的建立。