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三乙酰竹桃霉素在皮肤和软组织感染中的应用:一项新西兰全科医生多中心试验的结果

The use of triacetyloleandomycin in skin and soft tissue infections: results of a New Zealand general-practitioner multi-centre trial.

作者信息

Vaughan G P, Vaughan A M

出版信息

N Z Med J. 1977 Oct 26;86(598):385-6.

PMID:305017
Abstract

Fifty-one New Zealand general practitioners observed the treatment of 137 cases of skin and soft tissue infections with triacetyloleandomycin (TAO, Pfizer) over a five-month period. Nearly a third of these lesions occurred in children aged 10 years or less. "Excellent" or "good" results in 129 cases (94.2 percent) confirmed triacetyloleandomycin to be generally effective in these conditions. Twice-daily (12-hourly) oral administration proved as effective as more frequent dosage regimens and no major side-effects were encountered. Twenty cases with associated minor surgery are discussed separately.

摘要

51名新西兰全科医生在5个月的时间里观察了137例皮肤和软组织感染患者使用三乙酰竹桃霉素(TAO,辉瑞公司生产)的治疗情况。其中近三分之一的病例发生在10岁及以下的儿童身上。129例(94.2%)患者取得了“优秀”或“良好”的治疗效果,证实三乙酰竹桃霉素在这些病症中总体有效。每日两次(每12小时一次)口服给药与更频繁的给药方案效果相同,且未出现重大副作用。另外还单独讨论了20例伴有小手术的病例。

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