Department of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND.
Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH; Department of Biomedical Sciences, Ohio University, Athens, OH; Department of Geriatric Medicine, Ohio University, Athens, OH.
J Am Med Dir Assoc. 2019 Jun;20(6):730-735.e3. doi: 10.1016/j.jamda.2018.10.014. Epub 2018 Nov 28.
Impairments in specific tasks that are necessary for independent living may identify future self-care limitations, and the use of time-varying covariates can better capture the fluidity in functional capacity trajectories over time. The purpose of this study was to determine the associations between individual instrumental activities of daily living (IADL) impairments and time to activities of daily living (ADL) disability for middle-aged and older adults in the United States.
Longitudinal panel.
Detailed interviews that included physical, biological, and psychosocial measures were completed in person. The core interview was typically completed over the telephone.
A nationally representative sample of 15,336 adults aged at least 50 years from the 2006 wave of the Health and Retirement Study was followed for 8 years.
Ability to perform IADL and ADL were self-reported at each wave. Separate covariate-adjusted Cox models were used to examine the time-varying associations between individual IADL impairments and time to ADL disability.
The presence of each IADL impairment was associated with a higher hazard ratio for an ADL disability for the following functions: 2.52 [95% confidence interval (CI) 2.35, 2.70] for grocery shopping, 1.91 (CI 1.77, 2.06) for preparing hot meals, 1.55 (CI 1.37, 1.76) for taking medications, 1.48 (CI 1.36, 1.61) for managing money, 1.41 (CI 1.27, 1.57) for using a telephone, and 1.38 (CI 1.29, 1.48) for using a map.
CONCLUSIONS/IMPLICATIONS: Our findings provide insights into the disabling process by revealing how impairments in each IADL are differentially associated with time to ADL disability. Interventions aiming to retain function during aging should be informed by fluctuations in IADL performance and how specific IADL impairments may exacerbate functional capacity declines more so than others.
日常生活活动(ADL)中特定任务的损伤可能会识别出未来自理能力的局限性,并且使用时变协变量可以更好地捕捉功能能力轨迹随时间的变化。本研究的目的是确定美国中老年人个体工具性日常生活活动(IADL)损伤与 ADL 残疾时间之间的关联。
纵向面板。
详细的访谈包括身体、生物和社会心理测量,均亲自进行。核心访谈通常通过电话完成。
来自健康与退休研究 2006 年波的一个具有全国代表性的样本,共 15336 名年龄至少 50 岁的成年人,随访 8 年。
在每次随访中,均报告 IADL 和 ADL 的能力。使用单独的协变量调整 Cox 模型来检查个体 IADL 损伤与 ADL 残疾时间之间的时变关联。
每种 IADL 损伤的存在与 ADL 残疾的更高风险比相关,以下功能的风险比分别为:杂货店购物 2.52(95%置信区间 [CI] 2.35, 2.70)、准备热餐 1.91(CI 1.77, 2.06)、服用药物 1.55(CI 1.37, 1.76)、管理资金 1.48(CI 1.36, 1.61)、使用电话 1.41(CI 1.27, 1.57)和使用地图 1.38(CI 1.29, 1.48)。
结论/意义:我们的研究结果通过揭示每项 IADL 损伤如何与 ADL 残疾时间存在差异关联,提供了对失能过程的深入了解。旨在随着年龄增长保持功能的干预措施应该根据 IADL 表现的波动以及特定的 IADL 损伤如何比其他损伤更严重地加剧功能能力下降来提供信息。