Spera Leigh J, Danforth Rachel M, Hadad Ivan
Division of Plastic Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Transl Gastroenterol Hepatol. 2018 Oct 31;3:86. doi: 10.21037/tgh.2018.10.07. eCollection 2018.
Large intraabdominal, retroperitoneal, and abdominal wall sarcomas provide unique challenges in treatment due to their variable histology, potential considerable size at the time of diagnosis, and the ability to invade into critical structures. Historically, some of these tumors were considered inoperable if surgical access was limited or the consequential defect was unable to be closed primarily as reconstructive options were limited. Over time, there has been a greater understanding of the abdominal wall anatomy and mechanics, which has resulted in the development of new techniques to allow for sound oncologic resections and viable, durable options for abdominal wall reconstruction. Currently, intra-operative positioning and employment of a variety of abdominal and posterior trunk incisions have made more intraabdominal and retroperitoneal tumors accessible. Primary involvement or direct invasion of tumor into the abdominal wall is no longer prohibitive as utilization of advanced hernia repair techniques along with the application of vascularized tissue transfer have been shown to have the ability to repair large area defects involving multiple quadrants of the abdominal wall. Both local and distant free tissue transfer may be incorporated, depending on the size and location of the area needing reconstruction and what residual structures are remaining surrounding the resection bed. There is an emphasis on selecting the techniques that will be associated with the least amount of morbidity yet will restore and provide the appropriate structure and function necessary for the trunk. This review article summarizes both initial surgical incisional planning for the oncologic resection and a variety of repair options for the abdominal wall spanning the reconstructive ladder.
大的腹腔内、腹膜后和腹壁肉瘤在治疗中面临独特挑战,这是由于它们的组织学类型多样、诊断时可能体积相当大,以及具有侵犯关键结构的能力。从历史上看,如果手术入路受限或由于重建选择有限而导致的继发缺损无法一期闭合,其中一些肿瘤被认为无法手术切除。随着时间的推移,人们对腹壁解剖结构和力学有了更深入的了解,这促使了新技术的发展,从而能够进行合理的肿瘤切除,并为腹壁重建提供可行、持久的选择。目前,术中定位以及采用各种腹部和后躯干切口,使得更多的腹腔内和腹膜后肿瘤能够被触及。肿瘤对腹壁的原发性累及或直接侵犯不再是手术禁忌,因为先进的疝修补技术与带血管组织移植的应用已被证明有能力修复涉及腹壁多个象限的大面积缺损。根据需要重建区域的大小和位置以及切除床周围剩余的结构,可采用局部或远处游离组织移植。重点是选择那些发病率最低但能恢复并提供躯干所需适当结构和功能的技术。这篇综述文章总结了肿瘤切除的初始手术切口规划以及跨越重建阶梯的各种腹壁修复选择。