Manuele Riccardo, Senni Carlotta, Patil Kalpana, Taghizadeh Arash, Garriboli Massimo
Paediatric Urology, Evelina London Children's Hospital, London, UK.
Int Urol Nephrol. 2019 Feb;51(2):187-191. doi: 10.1007/s11255-018-2043-2. Epub 2018 Dec 1.
Foreskin reconstruction (FR) is a recognised, yet debated, option for patients undergoing single-stage hypospadias repair (HR).
We evaluated the incidence of complications after single-stage HR in our institution. This is a retrospective review of all single-stage HR. Patients were classified into group 1 (circumcision) and group 2 foreskin reconstruction (FR). Urethroplasty and foreskin complications were recorded. Statistics used are as follows: Mann-Whitney test to compare age at operation and length of follow-up (FU); Chi-Square test to analyse the incidence of urethral complications and need for reoperation; Log rank test to compare the survival curves; p statistically significant < 0.05. Data are presented as median (range).
304 patients were identified, operated between January 2010 and December 2016, and 20 were excluded: 6 already circumcised at the time of the surgery, 3 with megameatus intact prepuce, 11 lost at FU. 284 patients were included: 161 circumcised and 123 FR. Median age at the operation was 17 months (8-179) (group 1) and 17 months (8-148) (group 2) (p = 0.71). Length of FU was 19 months (8-91) (group 1) and 17 months (4-87) (group 2) (p = 0.45). The survival curve was homogeneous (p = 0.28). Urethroplasty complications occurred in 32/161 (20%) (group 1) and in 21/123 (17%) (group 2) (p = 0.55). Foreskin complications occurred in 18/123 (15%). A second operation was required in 33 boys in each group, (20% group 1 and 27% group 2) (p = 0.21).
FR does not increase the complication rate or the need for a reoperation after single-stage HR. Parents should be offered the option between the two procedures according to their personal preference.
对于接受一期尿道下裂修复术(HR)的患者而言,包皮重建术(FR)是一种已得到认可但仍存在争议的选择。
我们评估了本机构一期HR术后的并发症发生率。这是一项对所有一期HR手术的回顾性研究。患者被分为1组(包皮环切术)和2组(包皮重建术)。记录尿道成形术和包皮相关并发症。所使用的统计方法如下:采用曼-惠特尼检验比较手术年龄和随访时间(FU);采用卡方检验分析尿道并发症的发生率和再次手术的必要性;采用对数秩检验比较生存曲线;p<0.05具有统计学意义。数据以中位数(范围)表示。
共确定304例患者,于2010年1月至2016年12月期间接受手术,20例被排除:6例在手术时已行包皮环切术,3例为尿道口完整包皮过长,11例失访。纳入284例患者:161例行包皮环切术,123例行包皮重建术。手术时的中位年龄为17个月(8 - 179个月)(1组)和17个月(8 - 148个月)(2组)(p = 0.71)。随访时间为19个月(8 - 91个月)(1组)和17个月(4 - 87个月)(2组)(p = 0.45)。生存曲线具有同质性(p = 0.28)。尿道成形术并发症在161例中的32例(20%)(1组)和123例中的21例(17%)(2组)中出现(p = 0.55)。包皮并发症在123例中的18例(15%)中出现。每组有33名男孩需要再次手术(1组20%,2组27%)(p = 0.21)。
包皮重建术不会增加一期尿道下裂修复术后的并发症发生率或再次手术的必要性。应根据家长的个人偏好为其提供两种手术方式的选择。