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通过将手术经验转化为分类系统和复杂程度评分来提高枕骨大孔脑膜瘤患者的治疗效果。

Improving results in patients with foramen magnum meningiomas by translating surgical experience into a classification system and complexity score.

机构信息

Department of Neurosurgery, International Neuroscience Institute, Rudolf Pichlmayr Str. 4, 30625, Hannover, Germany.

Department of Human Neurosciences, Neurosurgery, University of Rome, "Sapienza", Rome, Italy.

出版信息

Neurosurg Rev. 2019 Dec;42(4):859-866. doi: 10.1007/s10143-018-01060-6. Epub 2018 Dec 1.

DOI:10.1007/s10143-018-01060-6
PMID:30506445
Abstract

Foramen magnum meningiomas (FMMs) are challenging lesions and controversy still exists regarding their optimal management. In the present paper, we propose some principles of surgical treatment of FMMs. We analyzed our series of 39 patients: the average maximum diameter was 31.1 mm (sd, 10.7). In two cases, there was extradural extension. We operated all anterior lesions through dorsolateral approach to craniovertebral junction and all posterior lesions through midline suboccipital approach and C1 laminectomy, following the prevalence of side of the tumor. There were no complications except for one case of post-operative hypoglossus paresis. We translated our experience with surgery of foramen magnum meningiomas into a classification system and a complexity score, in order to assign a score to each individual case and plan the surgical strategy. When the complexity score is 5 or more, we propose subtotal removal, in consideration of the benign nature.

摘要

枕骨大孔脑膜瘤(FMMs)是具有挑战性的病变,其最佳治疗方法仍存在争议。在本文中,我们提出了 FMMs 的手术治疗原则。我们分析了我们的 39 例患者系列:平均最大直径为 31.1mm(标准差,10.7)。在 2 例中,存在硬膜外延伸。我们通过颅颈交界部的外侧入路和中线枕下入路和 C1 椎板切除术对所有前病变进行手术,根据肿瘤的侧别进行操作。除 1 例术后舌下神经麻痹外,无其他并发症。我们将手术治疗枕骨大孔脑膜瘤的经验转化为一种分类系统和复杂性评分,以便对每个病例进行评分并制定手术策略。当复杂性评分为 5 分或更高时,我们建议进行次全切除,考虑到其良性性质。

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Endoscopic Endonasal and Transcranial Surgery for Microsurgical Resection of Ventral Foramen Magnum Meningiomas: A Preliminary Experience.内镜经鼻颅底手术切除颅底腹侧大孔脑膜瘤:初步经验。
Oper Neurosurg (Hagerstown). 2018 May 1;14(5):503-514. doi: 10.1093/ons/opx160.
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Surgical outcomes of craniocervial junction meningiomas: a series of 22 consecutive patients.颅颈交界区脑膜瘤的手术结果:22例连续病例系列
Clin Neurol Neurosurg. 2014 Feb;117:71-79. doi: 10.1016/j.clineuro.2013.11.023. Epub 2013 Dec 7.
3
Surgical management of ventral and ventrolateral foramen magnum meningiomas: report on a 64-case series and review of the literature.
颅颈交界区腹侧和腹外侧孔脑膜瘤的外科治疗:64 例病例系列报告及文献复习。
Neurosurg Rev. 2012 Jul;35(3):359-67; discussion 367-8. doi: 10.1007/s10143-012-0381-6. Epub 2012 Mar 21.
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Classification system of foramen magnum meningiomas.枕骨大孔脑膜瘤的分类系统
J Craniovertebr Junction Spine. 2010 Jan;1(1):10-7. doi: 10.4103/0974-8237.65476.
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Management of anterolateral foramen magnum meningiomas: surgical vs conservative decision making.前外侧枕骨大孔脑膜瘤的治疗:手术与保守决策。
Neurosurgery. 2010 Sep;67(3 Suppl Operative):ons58-70; discussion ons70. doi: 10.1227/01.NEU.0000382971.63877.DD.
6
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Surg Neurol. 2009 Oct;72(4):376-82; discussion 382. doi: 10.1016/j.surneu.2009.05.006. Epub 2009 Jul 15.
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Br J Neurosurg. 2009 Feb;23(1):33-9. doi: 10.1080/02688690802545932.
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