Dietze T R, Durrie D S
University of Nebraska Medical Center, Omaha.
Ophthalmology. 1988 Feb;95(2):236-46. doi: 10.1016/s0161-6420(88)33206-9.
Nineteen patients with keratoconus underwent epikeratophakia by one of the authors (DSD) and were followed from 3 to 29 months. Patient selection criteria included contact lens failure, and minimal or no central corneal scarring. Uncorrected visual acuity improved by three or more Snellen lines in 13 of 19 patients (68%). Postoperatively, after more than 6 months follow-up, 81% of the patients had best-corrected visual acuity of 20/40 or better. A mean flattening of 4.73 diopters (D) occurred on keratometry readings. There was a mean decrease in refractive cylinder of 2.84 D. Spherical equivalent refraction showed a mean decrease in myopia of 4.64 D. Five patients had postoperative refractive cylinder greater than 4 D requiring relaxing incision(s). With some patients having been followed for more than 2 years, no recurrences of keratoconus have been noted. In properly selected patients, epikeratophakia can effectively be used to treat keratoconus and thus avoid potential intraocular surgical complications and immunogenic phenomena.
19例圆锥角膜患者接受了由作者之一(DSD)实施的表层角膜镜片术,并随访了3至29个月。患者选择标准包括隐形眼镜矫正失败,以及角膜中央极少或无瘢痕形成。19例患者中有13例(68%)未矫正视力提高了3行或更多Snellen视力表行数。术后,经过超过6个月的随访,81%的患者最佳矫正视力达到20/40或更好。角膜曲率计读数平均变平4.73屈光度(D)。屈光柱镜平均降低2.84 D。等效球镜度显示近视平均降低4.64 D。5例患者术后屈光柱镜大于4 D,需要进行松解切口。部分患者已随访超过2年,未发现圆锥角膜复发。对于选择合适的患者,表层角膜镜片术可有效用于治疗圆锥角膜,从而避免潜在的眼内手术并发症和免疫原性现象。